C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: high mobility group box 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000067925 Hmgb2-201 ENSMUSG00000054717 10090 + 8:57511843-57515999 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000067925
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000067925 3.226±2.51 2.228±0.65 6.378±1.14 11.867±8.85 5.250±3.76 16.679±4.86 0.647±0.15 2.829±0.31 72.924±94.50 4.456±0.73 0.778±0.19 9.329±4.24 43.448±28.54 18.167±8.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BZ CIL_0008BZ_0002 VISTA 8:57035224-57635792
CIL_0008VG CIL_0008VG_0002 VISTA 8:57047180-57651136

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000793 ISS condensed chromosome
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0003684 IEA damaged DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0006288 ISS base-excision repair, DNA ligation
GO:0006357 ISS regulation of transcription from RNA polymerase II promoter
GO:0007283 IMP spermatogenesis
GO:0007289 IMP spermatid nucleus differentiation
GO:0008301 ISS DNA binding, bending
GO:0008584 IMP male gonad development
GO:0019904 IPI protein domain specific binding
GO:0032075 IEA positive regulation of nuclease activity
GO:0042056 IEA chemoattractant activity
GO:0043234 IEA protein complex
GO:0043388 IDA positive regulation of DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0044822 IEA poly(A) RNA binding
GO:0045648 IEA positive regulation of erythrocyte differentiation
GO:0045654 IEA positive regulation of megakaryocyte differentiation
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048471 ISS perinuclear region of cytoplasm
GO:0048545 IMP response to steroid hormone
GO:0050786 IEA RAGE receptor binding
GO:0050918 IEA positive chemotaxis
GO:0060326 IEA cell chemotaxis
GO:0071222 IEA cellular response to lipopolysaccharide
GO:1902042 IMP negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000296503 HMGB2-001 protein_coding Homo_sapiens 0 1208
ENST00000355832 ERCC6-001 protein_coding Homo_sapiens 0.0001 55
ENST00000438704 HMGB2-004 protein_coding Homo_sapiens 0 1136
ENST00000446922 HMGB2-003 protein_coding Homo_sapiens 0 1136
ENST00000447839 ERCC6-PGBD3-002 protein_coding Homo_sapiens 0.00006 55
ENST00000506267 HMGB2-005 protein_coding Homo_sapiens 0 503
ENST00000511316 HMGB2-002 retained_intron Homo_sapiens 0 538
ENST00000515869 ERCC6-PGBD3-001 protein_coding Homo_sapiens 0.00006 55
ENST00000591146 HMGB2P1-001 transcribed_processed_pseudogene Homo_sapiens 0 508

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