C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: methyltransferase like 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000298717 METTL3-001 ENSG00000165819 9606 - 14:21498138-21511375 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartKidneyLiverLungOvaryPlacentaTestisENST00000298717
Transcript ID Breast Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000298717 5.535±0.00 4.729±1.82 8.559±4.23 3.890±0.00 10.045±0.00 9.519±4.08 12.352±1.60 21.781±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008CX CIL_0008CX_0001 VISTA 14:21403052-22005074
CIL_0005QL CIL_0005QL_0001 CGP 14:21459020-21499175
CIL_0002HL CIL_0002HL_0001 CGP 14:21476597-21511375
CIL_0002HK CIL_0002HK_0001 CGP 14:21498133-21537216

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001510 IMP RNA methylation
GO:0003723 IEA RNA binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006139 IEA nucleobase-containing compound metabolic process
GO:0006397 ISS mRNA processing
GO:0007623 ISS circadian rhythm
GO:0008168 IEA methyltransferase activity
GO:0010467 TAS gene expression
GO:0016422 IMP mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
GO:0016607 IDA nuclear speck
GO:0019827 ISS stem cell maintenance
GO:0036396 IDA MIS complex
GO:0061157 ISS mRNA destabilization
GO:0080009 IMP mRNA methylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022767 Mettl3-001 protein_coding Mus_musculus 0 2383
ENSMUST00000174351 Mettl3-012 nonsense_mediated_decay Mus_musculus 0 1236
ENSMUST00000153539 Mettl3-003 nonsense_mediated_decay Mus_musculus 0 1184
ENSMUST00000147768 Mettl3-002 nonsense_mediated_decay Mus_musculus 0 998
ENSMUST00000173896 Mettl3-014 nonsense_mediated_decay Mus_musculus 0 961
ENSMUST00000122962 Mettl3-004 nonsense_mediated_decay Mus_musculus 0 911
ENSMUST00000174853 Mettl3-009 protein_coding Mus_musculus 0 837
ENSMUST00000156611 Mettl3-005 retained_intron Mus_musculus 0 749
ENSMUST00000127797 Mettl3-006 retained_intron Mus_musculus 0 560
ENSMUST00000173138 Mettl3-015 nonsense_mediated_decay Mus_musculus 0 472
ENSMUST00000173546 Mettl3-010 retained_intron Mus_musculus 0 444
ENSMUST00000174360 Mettl3-013 protein_coding Mus_musculus 0 366
ENSMUST00000130550 Mettl3-008 retained_intron Mus_musculus 0 257
ENSMUST00000145875 Mettl3-007 nonsense_mediated_decay Mus_musculus 0 209
ENSMUST00000173656 Mettl3-011 protein_coding Mus_musculus 0 191
ENSMUST00000022766 Tox4-001 protein_coding Mus_musculus 0 191

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