C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: hypoxia inducible factor 1, alpha subunit inhibitor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000299163 HIF1AN-002 ENSG00000166135 9606 + 10:100535859-100559998 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000299163
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000299163 2.530±0.00 1.983±0.00 0.676±0.00 2.130±0.89 2.430±1.35 3.203±0.00 2.187±1.55 2.216±1.78 1.343±0.16 1.200±0.46 4.029±2.49 3.704±1.75 3.067±1.08 7.327±0.80

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007QB CIL_0007QB_0001 VISTA 10:100185085-100786577
CIL_00082U CIL_00082U_0001 VISTA 10:100312457-100914449
CIL_00082V CIL_00082V_0001 VISTA 10:100315129-100915721
CIL_00093R CIL_00093R_0001 VISTA 10:100355158-100955821
CIL_00093O CIL_00093O_0001 VISTA 10:100359362-100959974
CIL_0008BC CIL_0008BC_0001 VISTA 10:100387324-100989228
CIL_0001CC CIL_0001CC_0002 CGP 10:100486642-100529881
CIL_0008BD CIL_0008BD_0001 VISTA 10:100486833-101088338
CIL_0007U1 CIL_0007U1_0001 VISTA 10:100491715-101092615
CIL_0005DQ CIL_0005DQ_0001 CGP 10:100523740-100559998
CIL_0005DR CIL_0005DR_0001 CGP 10:100529072-100829941

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005112 IPI Notch binding
GO:0005506 IDA iron ion binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IDA zinc ion binding
GO:0016706 EXP oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0019826 NAS oxygen sensor activity
GO:0031406 IDA carboxylic acid binding
GO:0036138 IDA peptidyl-histidine hydroxylation
GO:0036139 IDA peptidyl-histidine dioxygenase activity
GO:0036140 IDA peptidyl-asparagine 3-dioxygenase activity
GO:0042264 IDA peptidyl-aspartic acid hydroxylation
GO:0042265 IDA peptidyl-asparagine hydroxylation
GO:0042803 IDA protein homodimerization activity
GO:0045663 IDA positive regulation of myoblast differentiation
GO:0045746 IDA negative regulation of Notch signaling pathway
GO:0048037 IDA cofactor binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051059 IPI NF-kappaB binding
GO:0055114 IDA oxidation-reduction process
GO:0061418 TAS regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0061428 IDA negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071456 TAS cellular response to hypoxia
GO:0071532 IPI ankyrin repeat binding
GO:2001214 NAS positive regulation of vasculogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000040455 Hif1an-001 protein_coding Mus_musculus 0 1908
ENSMUST00000074912 2010012O05Rik-201 protein_coding Mus_musculus 0.000001 62

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