C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein disulfide isomerase family A, member 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000300289 PDIA3-001 ENSG00000167004 9606 + 15:43746392-43773279 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBreastLungOvaryENST00000300289
Transcript ID Bladder Breast Lung Ovary
ENST00000300289 2.513±0.00 6.315±0.00 7.487±0.00 23.480±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WI CIL_0007WI_0001 VISTA 15:43579049-44181693
CIL_00067X CIL_00067X_0001 CGP 15:43746392-43777543

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0003756 IBA protein disulfide isomerase activity
GO:0004197 TAS cysteine-type endopeptidase activity
GO:0004629 TAS phospholipase C activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005783 IDA:IEA endoplasmic reticulum
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005790 IEA smooth endoplasmic reticulum
GO:0005925 IDA focal adhesion
GO:0006457 IBA protein folding
GO:0006508 TAS proteolysis
GO:0006606 TAS protein import into nucleus
GO:0006621 TAS protein retention in ER lumen
GO:0007165 TAS signal transduction
GO:0009986 IDA cell surface
GO:0016853 IEA isomerase activity
GO:0018279 TAS protein N-linked glycosylation via asparagine
GO:0034976 IBA response to endoplasmic reticulum stress
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045454 IEA cell redox homeostasis
GO:0070062 IDA extracellular vesicular exosome
GO:2001238 IEA positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000028683 Pdia3-001 protein_coding Mus_musculus 0 2058
ENSMUST00000135079 Pdia3-004 nonsense_mediated_decay Mus_musculus 0 551
ENSMUST00000130450 Pdia3-002 retained_intron Mus_musculus 0 431
ENSMUST00000140752 Serinc4-005 nonsense_mediated_decay Mus_musculus 3e-33 148
ENSMUST00000116432 Ell3-201 protein_coding Mus_musculus 3e-33 148
ENSMUST00000028679 Ell3-001 protein_coding Mus_musculus 3e-33 148
ENSDART00000020252 pdip5-001 protein_coding Danio_rerio 0.000000009 68

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