C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sterol O-acyltransferase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000301466 SOAT2-001 ENSG00000167780 9606 + 12:53103518-53124538 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalLiverOvaryTestisENST00000301466
Transcript ID Adrenal Liver Ovary Testis
ENST00000301466 0.064±0.00 0.040±0.00 0.118±0.00 0.080±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006TD CIL_0006TD_0001 CGP 12:53097436-53124538
CIL_0006TC CIL_0006TC_0001 CGP 12:53103518-53180909

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000062 IDA fatty-acyl-CoA binding
GO:0004772 IEA sterol O-acyltransferase activity
GO:0005783 IDA endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005903 IDA brush border
GO:0008203 IDA cholesterol metabolic process
GO:0010742 TAS macrophage derived foam cell differentiation
GO:0015485 IDA cholesterol binding
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016746 TAS transferase activity, transferring acyl groups
GO:0030299 IC intestinal cholesterol absorption
GO:0033344 IMP cholesterol efflux
GO:0034379 IMP very-low-density lipoprotein particle assembly
GO:0034435 IDA cholesterol esterification
GO:0034736 IDA cholesterol O-acyltransferase activity
GO:0042632 TAS cholesterol homeostasis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023806 Soat2-001 protein_coding Mus_musculus 0 1465
ENSMUST00000160465 Soat2-002 nonsense_mediated_decay Mus_musculus 0 745

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