C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000302539 ABCC8-201 ENSG00000006071 9606 - 11:17392886-17476845 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartLiverOvaryPlacentaTestisENST00000302539
Transcript ID Brain Heart Liver Ovary Placenta Testis
ENST00000302539 0.863±0.16 0.132±0.10 0.009±0.00 0.037±0.00 0.019±0.00 0.192±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003ZU CIL_0003ZU_0001 CGP 11:17385859-17476845
CIL_0003ZZ CIL_0003ZZ_0001 CGP 11:17392885-17544416

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0005975 NAS carbohydrate metabolic process
GO:0006112 TAS energy reserve metabolic process
GO:0006200 IEA ATP catabolic process
GO:0006810 IEA transport
GO:0006813 TAS potassium ion transport
GO:0007165 IEA signal transduction
GO:0007268 TAS synaptic transmission
GO:0008076 IDA voltage-gated potassium channel complex
GO:0008281 IEA sulfonylurea receptor activity
GO:0015079 TAS potassium ion transmembrane transporter activity
GO:0016021 IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0042626 IEA ATPase activity, coupled to transmembrane movement of substances
GO:0044281 TAS small molecule metabolic process
GO:0044325 IPI ion channel binding
GO:0050796 TAS regulation of insulin secretion
GO:0055085 TAS:IEA transmembrane transport
GO:0071805 TAS potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033123 Abcc8-201 protein_coding Mus_musculus 0 5980
ENSDART00000088191 ABCC8 (2 of 3)-201 protein_coding Danio_rerio 0 448

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