C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dihydropyrimidine dehydrogenase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000306031 DPYD-002 ENSG00000188641 9606 - 1:97719758-97921049 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainENST00000306031
Transcript ID Brain
ENST00000306031 0.674±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007J2 CIL_0007J2_0001 UCNEbase 1:95311769-97837577
CIL_0007C5 CIL_0007C5_0002 CGP 1:96721665-97921049
CIL_0008IK CIL_0008IK_0001 VISTA 1:96844935-97446185

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004152 IEA dihydroorotate dehydrogenase activity
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006145 IMP purine nucleobase catabolic process
GO:0006206 TAS pyrimidine nucleobase metabolic process
GO:0006208 ISS pyrimidine nucleobase catabolic process
GO:0006210 IDA thymine catabolic process
GO:0006212 IDA uracil catabolic process
GO:0006214 IDA thymidine catabolic process
GO:0006222 IEA UMP biosynthetic process
GO:0017113 ISS dihydropyrimidine dehydrogenase (NADP+) activity
GO:0019483 IEA beta-alanine biosynthetic process
GO:0042803 ISS protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0046135 TAS pyrimidine nucleoside catabolic process
GO:0046872 IEA metal ion binding
GO:0050660 ISS flavin adenine dinucleotide binding
GO:0050661 ISS NADP binding
GO:0051536 IEA iron-sulfur cluster binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000150950 Dpyd-002 retained_intron Mus_musculus 0 558
ENSMUST00000126254 Dpyd-003 retained_intron Mus_musculus 0 558
ENSMUST00000039177 Dpyd-001 protein_coding Mus_musculus 0 558
ENSMUST00000149101 Dpyd-004 retained_intron Mus_musculus 0 291

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