C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: cholinergic receptor, nicotinic, beta 1 (muscle)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000306071 CHRNB1-001 ENSG00000170175 9606 + 17:7445061-7457707 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306071
Transcript ID Adipose Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306071 0.377±0.00 1.300±0.00 1.091±0.59 1.350±0.00 1.444±1.14 1.315±0.00 0.479±0.36 17.142±5.02 1.907±0.00 6.393±3.16 3.258±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006ST CIL_0006ST_0002 CGP 17:7438273-7457707

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001941 IMP postsynaptic membrane organization
GO:0003009 IEA skeletal muscle contraction
GO:0004889 ISS acetylcholine-activated cation-selective channel activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0005892 IMP acetylcholine-gated channel complex
GO:0006810 IEA transport
GO:0006811 IEA ion transport
GO:0006812 IMP cation transport
GO:0006936 IMP muscle contraction
GO:0007165 IMP signal transduction
GO:0007271 IMP synaptic transmission, cholinergic
GO:0007274 IMP neuromuscular synaptic transmission
GO:0015267 IMP channel activity
GO:0015276 ISS ligand-gated ion channel activity
GO:0015464 IMP acetylcholine receptor activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0034220 ISS ion transmembrane transport
GO:0035095 IMP behavioral response to nicotine
GO:0042166 ISS acetylcholine binding
GO:0042391 ISS regulation of membrane potential
GO:0045202 IMP synapse
GO:0045211 IEA postsynaptic membrane
GO:0048747 IMP muscle fiber development
GO:0050877 IMP neurological system process
GO:0055085 IMP transmembrane transport
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000045971 Chrnb1-001 protein_coding Mus_musculus 0 1618
ENSMUST00000154816 Chrnb1-003 retained_intron Mus_musculus 0 477
ENSMUST00000147791 Chrnb1-002 processed_transcript Mus_musculus 0 424

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