C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sorbin and SH3 domain containing 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000306402 SORBS1-001 ENSG00000095637 9606 - 10:95311773-95561414 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLungOvaryPlacentaTestisENST00000306402
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Lung Ovary Placenta Testis
ENST00000306402 21.555±0.00 14.944±0.00 0.670±0.00 7.072±2.91 81.851±0.00 11.821±0.00 4.579±0.00 4.072±0.00 2.973±1.42 5.167±3.42 10.553±6.24

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00095J CIL_00095J_0001 VISTA 10:95113366-95716533
CIL_0007T2 CIL_0007T2_0001 VISTA 10:95207959-95809585
CIL_00067J CIL_00067J_0001 CGP 10:95237572-95561414
CIL_00067I CIL_00067I_0001 CGP 10:95311771-95656706

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001725 ISS stress fiber
GO:0003779 TAS actin binding
GO:0005070 IC SH3/SH2 adaptor activity
GO:0005158 IDA insulin receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005829 ISS cytosol
GO:0005899 IDA insulin receptor complex
GO:0005913 ISS cell-cell adherens junction
GO:0005915 TAS zonula adherens
GO:0005924 ISS cell-substrate adherens junction
GO:0006936 TAS muscle contraction
GO:0007160 TAS cell-matrix adhesion
GO:0008092 TAS cytoskeletal protein binding
GO:0008286 ISS insulin receptor signaling pathway
GO:0009967 IC positive regulation of signal transduction
GO:0015758 ISS glucose transport
GO:0032869 ISS cellular response to insulin stimulus
GO:0043149 ISS stress fiber assembly
GO:0045121 ISS membrane raft
GO:0045725 ISS positive regulation of glycogen biosynthetic process
GO:0046326 ISS positive regulation of glucose import
GO:0046889 ISS positive regulation of lipid biosynthetic process
GO:0048041 ISS focal adhesion assembly
GO:0090004 ISS positive regulation of establishment of protein localization to plasma membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000099466 Sorbs1-201 protein_coding Mus_musculus 0 2394
ENSMUST00000165469 Sorbs1-204 protein_coding Mus_musculus 0 1221
ENSMUST00000165212 Sorbs1-203 protein_coding Mus_musculus 0 933
ENSMUST00000099467 Sorbs1-202 protein_coding Mus_musculus 0 933

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