C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: WNK lysine deficient protein kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000315939 WNK1-001 ENSG00000060237 9606 + 12:752923-911452 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastHeartLiverMuscleOvaryPlacentaTestisENST00000315939
Transcript ID Adrenal Bladder Brain Breast Heart Liver Muscle Ovary Placenta Testis
ENST00000315939 1.882±0.00 5.150±0.00 2.906±0.00 2.832±0.00 13.059±6.47 4.170±0.00 2.366±0.00 5.533±2.73 1.317±0.31 9.896±2.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008AW CIL_0008AW_0001 VISTA 12:291137-892234
CIL_0007TY CIL_0007TY_0001 VISTA 12:564896-1165613

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004860 IEA protein kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0006468 IDA:IEA protein phosphorylation
GO:0006469 IEA negative regulation of protein kinase activity
GO:0006811 ISS ion transport
GO:0010923 IDA negative regulation of phosphatase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018107 TAS peptidyl-threonine phosphorylation
GO:0019869 IDA chloride channel inhibitor activity
GO:0019902 IDA phosphatase binding
GO:0035556 IDA intracellular signal transduction
GO:0048666 NAS neuron development
GO:0050794 ISS regulation of cellular process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000060043 Wnk1-001 protein_coding Mus_musculus 0 7978
ENSMUST00000088644 Wnk1-201 protein_coding Mus_musculus 0 4593
ENSMUST00000177761 Wnk1-203 protein_coding Mus_musculus 0 4237
ENSMUST00000088646 Wnk1-202 protein_coding Mus_musculus 0 2894
ENSMUST00000159397 Wnk1-005 retained_intron Mus_musculus 0 2894
ENSMUST00000161048 Wnk1-004 protein_coding Mus_musculus 0 1347
ENSMUST00000160769 Wnk1-003 retained_intron Mus_musculus 0 1236
ENSMUST00000159903 Wnk1-002 retained_intron Mus_musculus 0 883
ENSMUST00000161243 Wnk1-015 protein_coding Mus_musculus 0 869
ENSMUST00000159785 Wnk1-009 protein_coding Mus_musculus 0 754
ENSMUST00000161185 Wnk1-011 retained_intron Mus_musculus 0 691
ENSMUST00000160493 Wnk1-019 protein_coding Mus_musculus 0 617
ENSMUST00000161392 Wnk1-018 processed_transcript Mus_musculus 0 486
ENSMUST00000159151 Wnk1-007 retained_intron Mus_musculus 0 472
ENSMUST00000035513 Wnk1-006 processed_transcript Mus_musculus 0 472
ENSMUST00000162368 Wnk1-010 protein_coding Mus_musculus 0 377
ENSMUST00000160872 Wnk1-014 protein_coding Mus_musculus 2e-28 134
ENSMUST00000162190 Wnk1-013 protein_coding Mus_musculus 9e-28 132

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