C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cullin 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000325222 CUL1-002 ENSG00000055130 9606 + 7:148698912-148801036 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000325222
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000325222 18.165±0.00 15.436±0.00 1.065±0.00 11.165±7.95 6.533±3.41 9.969±7.04 7.709±6.79 9.784±3.23 6.109±1.99 6.616±3.45 14.042±10.24 12.247±3.88 12.698±0.14 22.088±9.29

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004XU CIL_0004XU_0001 CGP 7:148697914-148884321

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0005515 IPI protein binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006513 IEA protein monoubiquitination
GO:0006915 IEA apoptotic process
GO:0007050 TAS cell cycle arrest
GO:0007219 TAS Notch signaling pathway
GO:0008283 IEA cell proliferation
GO:0008285 TAS negative regulation of cell proliferation
GO:0009887 IEA organ morphogenesis
GO:0016032 IEA viral process
GO:0016567 IDA protein ubiquitination
GO:0019005 ISS SCF ubiquitin ligase complex
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031146 ISS SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031461 IDA:IEA cullin-RING ubiquitin ligase complex
GO:0031625 IEA ubiquitin protein ligase binding
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1990452 IPI Parkin-FBXW7-Cul1 ubiquitin ligase complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000031697 Cul1-001 protein_coding Mus_musculus 0 3709
ENSMUST00000146200 Cul1-002 protein_coding Mus_musculus 0 3011
ENSMUST00000146828 Cul1-004 protein_coding Mus_musculus 0 577
ENSMUST00000149531 Cul1-008 processed_transcript Mus_musculus 0 556
ENSMUST00000151934 Cul1-010 retained_intron Mus_musculus 0 534
ENSMUST00000143941 Cul1-003 processed_transcript Mus_musculus 0 333
ENSMUST00000154391 Cul1-006 processed_transcript Mus_musculus 0 326
ENSMUST00000152547 Cul1-005 protein_coding Mus_musculus 0 246
ENSMUST00000126877 Cul1-009 processed_transcript Mus_musculus 0 235
ENSMUST00000154201 Cul1-007 retained_intron Mus_musculus 4e-26 124

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