C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: X-ray repair complementing defective repair in Chinese hamster cells 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000338635 XRCC4-002 ENSG00000152422 9606 + 5:83077527-83353711 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000338635
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000338635 1.083±0.00 0.967±0.00 0.473±0.00 1.302±0.24 1.031±0.56 1.276±0.00 1.641±0.00 0.563±0.00 0.999±0.00 0.317±0.00 0.402±0.00 2.170±1.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005TL CIL_0005TL_0002 CGP 5:83052846-83353787

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005813 IDA centrosome
GO:0005829 IDA cytosol
GO:0005958 IDA DNA-dependent protein kinase-DNA ligase 4 complex
GO:0006281 TAS DNA repair
GO:0006302 IDA:IEA double-strand break repair
GO:0006303 IDA double-strand break repair via nonhomologous end joining
GO:0006310 IEA DNA recombination
GO:0008022 IPI protein C-terminus binding
GO:0010165 IDA response to X-ray
GO:0016032 TAS viral process
GO:0030054 IDA cell junction
GO:0032807 IDA DNA ligase IV complex
GO:0051103 IDA DNA ligation involved in DNA repair
GO:0051351 IDA positive regulation of ligase activity
GO:0070419 IDA nonhomologous end joining complex
GO:0075713 TAS establishment of integrated proviral latency

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022115 Xrcc4-001 protein_coding Mus_musculus 0 771
ENSMUST00000159199 Xrcc4-002 nonsense_mediated_decay Mus_musculus 0 682
ENSMUST00000160232 Xrcc4-003 protein_coding Mus_musculus 0 246
ENSMUST00000161396 Xrcc4-004 protein_coding Mus_musculus 0 237

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