C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: alkaline ceramidase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000340967 ACER2-001 ENSG00000177076 9606 + 9:19409059-19452020 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryENST00000340967
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary
ENST00000340967 0.689±0.00 0.536±0.00 0.925±0.00 0.439±0.00 0.167±0.00 0.683±0.35 3.048±2.79 0.954±0.30 0.125±0.03 0.440±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007DC CIL_0007DC_0001 CGP 9:19375715-19452020
CIL_0007DB CIL_0007DB_0001 CGP 9:19409059-19786928

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0001953 IDA negative regulation of cell-matrix adhesion
GO:0005794 IDA Golgi apparatus
GO:0006665 TAS sphingolipid metabolic process
GO:0006672 IEA ceramide metabolic process
GO:0006919 IMP activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0008284 IDA positive regulation of cell proliferation
GO:0010942 IMP positive regulation of cell death
GO:0016021 IEA integral component of membrane
GO:0016811 IEA hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0017040 IDA ceramidase activity
GO:0030148 TAS sphingolipid biosynthetic process
GO:0030173 IDA integral component of Golgi membrane
GO:0032526 IDA response to retinoic acid
GO:0033629 IDA negative regulation of cell adhesion mediated by integrin
GO:0035690 IEP cellular response to drug
GO:0044281 TAS small molecule metabolic process
GO:0046512 IDA sphingosine biosynthetic process
GO:0071633 IDA dihydroceramidase activity
GO:0090285 IMP negative regulation of protein glycosylation in Golgi

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000045224 Acer2-001 protein_coding Mus_musculus 0 1046
ENSMUST00000128712 Acer2-003 processed_transcript Mus_musculus 0 802
ENSMUST00000084433 Acer2-002 protein_coding Mus_musculus 0 514

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