C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sphingomyelin phosphodiesterase 1, acid lysosomal
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000342245 SMPD1-001 ENSG00000166311 9606 + 11:6390431-6394995 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000342245
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000342245 7.480±0.00 8.963±0.00 1.860±0.00 8.753±4.54 3.148±2.06 0.861±0.00 7.042±5.56 17.162±8.90 18.292±16.27 7.327±0.00 5.524±3.44 9.294±7.22 28.036±12.13 0.798±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00079D CIL_00079D_0001 CGP 11:6318946-6394998
CIL_0004AE CIL_0004AE_0001 CGP 11:6390431-6419414

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004767 IEA sphingomyelin phosphodiesterase activity
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0006665 TAS sphingolipid metabolic process
GO:0006684 TAS sphingomyelin metabolic process
GO:0006685 IEA sphingomyelin catabolic process
GO:0006687 TAS glycosphingolipid metabolic process
GO:0007165 TAS signal transduction
GO:0007399 TAS nervous system development
GO:0008219 IEA cell death
GO:0016787 IEA hydrolase activity
GO:0016798 IEA hydrolase activity, acting on glycosyl bonds
GO:0023021 IMP termination of signal transduction
GO:0035307 IMP positive regulation of protein dephosphorylation
GO:0042220 IEA response to cocaine
GO:0042493 IEA response to drug
GO:0042599 IEA lamellar body
GO:0043065 IEA positive regulation of apoptotic process
GO:0043202 TAS lysosomal lumen
GO:0043407 IMP negative regulation of MAP kinase activity
GO:0044281 TAS small molecule metabolic process
GO:0046513 IMP ceramide biosynthetic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000046983 Smpd1-201 protein_coding Mus_musculus 0 1727

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