C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sphingomyelin phosphodiesterase 1, acid lysosomal
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000046983 Smpd1-201 ENSMUSG00000037049 10090 + 7:105554360-105558388 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000046983
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000046983 36.850±10.49 39.305±2.23 15.185±0.48 18.116±1.87 30.885±5.51 21.326±0.74 61.966±6.67 51.758±7.36 16.891±7.56 41.019±2.43 25.189±0.77 20.987±5.13 27.581±9.59 1.539±0.60

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00079D CIL_00079D_0002 CGP 7:105480607-105558388
CIL_0004AE CIL_0004AE_0002 CGP 7:105554360-105581653

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004767 IEA sphingomyelin phosphodiesterase activity
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005764 IEA lysosome
GO:0006685 IEA sphingomyelin catabolic process
GO:0016798 IEA hydrolase activity, acting on glycosyl bonds
GO:0023021 IEA termination of signal transduction
GO:0035307 IEA positive regulation of protein dephosphorylation
GO:0042220 IEA response to cocaine
GO:0042493 IEA response to drug
GO:0042599 IEA lamellar body
GO:0043065 IEA positive regulation of apoptotic process
GO:0043407 IEA negative regulation of MAP kinase activity
GO:0046513 IEA ceramide biosynthetic process
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000342245 SMPD1-001 protein_coding Homo_sapiens 0 1727
ENST00000526280 SMPD1-004 protein_coding Homo_sapiens 0 643
ENST00000527275 SMPD1-008 protein_coding Homo_sapiens 0 1690
ENST00000531303 SMPD1-003 nonsense_mediated_decay Homo_sapiens 0 806
ENST00000531336 SMPD1-006 retained_intron Homo_sapiens 0 390
ENST00000533123 SMPD1-002 nonsense_mediated_decay Homo_sapiens 0 643
ENST00000534405 SMPD1-007 nonsense_mediated_decay Homo_sapiens 0 883

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