C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: FYVE, RhoGEF and PH domain containing 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000343958 FGD6-001 ENSG00000180263 9606 - 12:95076749-95217464 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343958
Transcript ID Adipose Adrenal Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343958 0.399±0.00 0.124±0.00 0.540±0.13 0.864±0.14 0.633±0.22 0.366±0.14 0.751±0.55 1.781±0.32 0.256±0.06 0.975±0.72 0.412±0.13 1.025±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005XD CIL_0005XD_0002 CGP 12:95020229-95217482
CIL_0000Y0 CIL_0000Y0_0002 CGP 12:95076749-95302790

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001726 ISS ruffle
GO:0005085 ISS guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005737 ISS cytoplasm
GO:0005794 ISS Golgi apparatus
GO:0005856 IEA cytoskeleton
GO:0007010 ISS cytoskeleton organization
GO:0008360 ISS regulation of cell shape
GO:0030027 ISS lamellipodium
GO:0030036 ISS actin cytoskeleton organization
GO:0031267 ISS small GTPase binding
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043088 ISS regulation of Cdc42 GTPase activity
GO:0043547 ISS positive regulation of GTPase activity
GO:0046847 ISS filopodium assembly
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020208 Fgd6-001 protein_coding Mus_musculus 0 2737
ENSMUST00000141143 Fgd6-002 processed_transcript Mus_musculus 0 220
ENSMUST00000125535 Fgd6-003 retained_intron Mus_musculus 8e-23 115

Loading