C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: isocitrate dehydrogenase 1 (NADP+), soluble
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000345146 IDH1-001 ENSG00000138413 9606 - 2:208236227-208255133 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000345146
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000345146 36.593±0.00 13.359±0.00 7.408±0.00 4.474±0.03 42.338±35.47 14.784±2.58 4.435±0.63 40.200±17.71 34.310±24.45 7.867±0.14 0.939±0.28 35.880±14.01 39.693±3.76 23.489±2.30

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00045J CIL_00045J_0001 CGP 2:208165343-208266074
CIL_00014C CIL_00014C_0001 CGP 2:208236227-208358751

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0004450 IDA:IEA isocitrate dehydrogenase (NADP+) activity
GO:0005102 IPI receptor binding
GO:0005737 IDA cytoplasm
GO:0005777 IDA peroxisome
GO:0005782 TAS peroxisomal matrix
GO:0005829 IDA cytosol
GO:0006097 IEA glyoxylate cycle
GO:0006099 IEA tricarboxylic acid cycle
GO:0006102 IEA:IDA isocitrate metabolic process
GO:0006103 IDA 2-oxoglutarate metabolic process
GO:0006740 TAS NADPH regeneration
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042803 IPI protein homodimerization activity
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000169032 Idh1-201 protein_coding Mus_musculus 0 1873
ENSMUST00000097709 Idh1-001 protein_coding Mus_musculus 0 1871
ENSMUST00000188109 Idh1-003 protein_coding Mus_musculus 0 824
ENSMUST00000188876 Idh1-004 protein_coding Mus_musculus 0 747
ENSMUST00000149310 Idh1-002 protein_coding Mus_musculus 0 566
ENSMUST00000186222 Idh1-006 protein_coding Mus_musculus 0 335

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