C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tousled-like kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000346027 TLK2-001 ENSG00000146872 9606 + 17:62479025-62613490 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000346027
Transcript ID Adipose Brain Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000346027 1.586±0.00 3.032±0.00 1.779±0.09 0.893±0.10 0.528±0.00 2.396±0.00 3.574±0.00 2.504±0.89 1.415±0.23 10.831±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00056B CIL_00056B_0002 CGP 17:62423867-62615481
CIL_000563 CIL_000563_0002 CGP 17:62458658-62693597

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001672 IDA regulation of chromatin assembly or disassembly
GO:0004672 IEA protein kinase activity
GO:0004674 IEA:IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA:IDA ATP binding
GO:0005634 IEA:IDA nucleus
GO:0005730 IDA nucleolus
GO:0005882 IDA intermediate filament
GO:0006468 IEA:IDA protein phosphorylation
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007049 IEA cell cycle
GO:0007059 IMP chromosome segregation
GO:0010507 NAS negative regulation of autophagy
GO:0016568 IEA chromatin modification
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0032435 IMP negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556 IDA intracellular signal transduction
GO:0048471 IDA perinuclear region of cytoplasm
GO:0071480 IDA cellular response to gamma radiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000106941 Tlk2-006 protein_coding Mus_musculus 0 4998
ENSMUST00000106939 Tlk2-001 protein_coding Mus_musculus 0 4071
ENSMUST00000126175 Tlk2-003 nonsense_mediated_decay Mus_musculus 0 4069
ENSMUST00000015107 Tlk2-008 protein_coding Mus_musculus 0 4069
ENSMUST00000092537 Tlk2-002 protein_coding Mus_musculus 0 3338
ENSMUST00000145048 Tlk2-009 protein_coding Mus_musculus 0 2073
ENSMUST00000146910 Tlk2-007 processed_transcript Mus_musculus 0 922
ENSMUST00000152404 Tlk2-005 protein_coding Mus_musculus 0 846
ENSMUST00000121771 Gm13168-001 processed_pseudogene Mus_musculus 0 780
ENSMUST00000120042 Gm13240-001 processed_pseudogene Mus_musculus 0 725
ENSMUST00000120609 Gm13161-001 processed_pseudogene Mus_musculus 0 725
ENSMUST00000117481 Gm13243-001 processed_pseudogene Mus_musculus 0 725
ENSMUST00000149459 Tlk2-011 protein_coding Mus_musculus 0 418
ENSMUST00000126054 Tlk2-010 retained_intron Mus_musculus 0 392
ENSMUST00000121481 Gm13162-001 processed_pseudogene Mus_musculus 0 366
ENSMUST00000134419 Tlk2-012 retained_intron Mus_musculus 0 357
ENSMUST00000123050 Tlk2-004 retained_intron Mus_musculus 0 340

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