C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000368305 LAMTOR2-001 ENSG00000116586 9606 + 1:156054752-156058510 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368305
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368305 29.713±0.00 46.999±0.00 1.871±0.00 13.111±2.14 24.462±21.48 23.253±20.43 9.116±6.22 29.240±15.74 33.043±29.46 18.245±15.84 23.327±16.71 41.498±22.46 47.644±23.47 17.360±6.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000898 CIL_000898_0001 VISTA 1:155789635-156392759
CIL_0008P5 CIL_0008P5_0001 VISTA 1:155795688-156399252

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000186 IEA activation of MAPKK activity
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005765 IDA lysosomal membrane
GO:0005770 ISS late endosome
GO:0016049 IMP cell growth
GO:0032008 IMP positive regulation of TOR signaling
GO:0032947 IDA protein complex scaffold
GO:0034613 IMP cellular protein localization
GO:0043547 IDA positive regulation of GTPase activity
GO:0070062 IDA extracellular vesicular exosome
GO:0071230 IMP cellular response to amino acid stimulus
GO:0071986 IDA Ragulator complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000029698 Lamtor2-001 protein_coding Mus_musculus 0 551
ENSMUST00000119002 Lamtor2-003 protein_coding Mus_musculus 0 427
ENSMUST00000145172 Lamtor2-002 retained_intron Mus_musculus 0 339
ENSMUST00000156421 Lamtor2-004 processed_transcript Mus_musculus 2e-27 126

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