C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000029698 Lamtor2-001 ENSMUSG00000028062 10090 - 3:88549819-88553024 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029698
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029698 55.879±9.41 34.806±9.36 62.636±1.96 57.208±22.78 35.805±11.00 56.138±11.30 37.670±7.67 99.096±16.29 91.102±17.21 53.325±3.66 40.278±4.20 46.438±29.86 113.220±86.12 20.906±3.24

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008P5 CIL_0008P5_0002 VISTA 3:88218217-88823366
CIL_000898 CIL_000898_0002 VISTA 3:88224783-88827970
CIL_00064T CIL_00064T_0002 CGP 3:88549819-88569725

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000186 IDA activation of MAPKK activity
GO:0005085 ISS guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005765 IEA lysosomal membrane
GO:0005770 IDA late endosome
GO:0016049 ISS cell growth
GO:0032008 ISS positive regulation of TOR signaling
GO:0032947 ISS protein complex scaffold
GO:0034613 ISS cellular protein localization
GO:0043547 ISS positive regulation of GTPase activity
GO:0070062 IEA extracellular vesicular exosome
GO:0071230 ISS cellular response to amino acid stimulus
GO:0071986 ISS Ragulator complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000058325 lamtor2-001 protein_coding Danio_rerio 0 255
ENST00000368302 LAMTOR2-003 protein_coding Homo_sapiens 0 462
ENST00000368304 LAMTOR2-002 protein_coding Homo_sapiens 0 339
ENST00000368305 LAMTOR2-001 protein_coding Homo_sapiens 0 551
ENST00000487106 LAMTOR2-004 processed_transcript Homo_sapiens 0 427
ENST00000489664 LAMTOR2-005 processed_transcript Homo_sapiens 0 339

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