C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cathepsin S
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000368985 CTSS-001 ENSG00000163131 9606 - 1:150730196-150765957 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000368985
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000368985 9.478±0.00 18.824±0.00 0.223±0.00 0.893±0.49 2.866±0.03 3.821±0.92 0.797±0.58 3.317±0.38 3.159±1.26 13.405±4.45 0.587±0.00 2.934±1.39 4.804±1.63

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001968 IPI fibronectin binding
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002250 IEP adaptive immune response
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002480 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0004197 IDA cysteine-type endopeptidase activity
GO:0005518 IDA collagen binding
GO:0005576 NAS extracellular region
GO:0005615 IDA extracellular space
GO:0005764 IDA lysosome
GO:0006508 TAS:IEA proteolysis
GO:0006955 TAS immune response
GO:0008233 IEA peptidase activity
GO:0008234 IEA cysteine-type peptidase activity
GO:0016020 IEA membrane
GO:0019882 TAS antigen processing and presentation
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0030574 IDA collagen catabolic process
GO:0034769 IDA basement membrane disassembly
GO:0036021 TAS endolysosome lumen
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0043202 TAS lysosomal lumen
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043236 IDA laminin binding
GO:0043394 IPI proteoglycan binding
GO:0045087 TAS innate immune response
GO:0050729 IEA positive regulation of inflammatory response
GO:0051603 IDA proteolysis involved in cellular protein catabolic process
GO:0097067 IEP cellular response to thyroid hormone stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000116304 Ctss-201 protein_coding Mus_musculus 0 867
ENSMUST00000015667 Ctss-001 protein_coding Mus_musculus 0 867

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