C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: NADPH oxidase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000372966 NOX1-001 ENSG00000007952 9606 - X:100843324-100874345 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonOvaryTestisENST00000372966
Transcript ID Colon Ovary Testis
ENST00000372966 3.245±2.53 2.610±1.31 0.009±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000YO CIL_0000YO_0002 CGP X:100820359-100874345
CIL_0007B9 CIL_0007B9_0001 CGP X:100843324-100929433

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0003081 IEA regulation of systemic arterial blood pressure by renin-angiotensin
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005768 IEA endosome
GO:0005769 IDA early endosome
GO:0006739 IC NADP metabolic process
GO:0006801 IMP superoxide metabolic process
GO:0006954 TAS inflammatory response
GO:0007165 TAS signal transduction
GO:0008217 TAS regulation of blood pressure
GO:0008284 IDA positive regulation of cell proliferation
GO:0010575 IEP positive regulation vascular endothelial growth factor production
GO:0015992 IDA proton transport
GO:0016021 IC integral component of membrane
GO:0016175 IC superoxide-generating NADPH oxidase activity
GO:0016477 IMP cell migration
GO:0016491 IEA oxidoreductase activity
GO:0030054 IEA cell junction
GO:0030171 IDA voltage-gated proton channel activity
GO:0030198 IEA extracellular matrix organization
GO:0034765 IEA regulation of ion transmembrane transport
GO:0042554 IDA superoxide anion generation
GO:0042743 IDA hydrogen peroxide metabolic process
GO:0043020 IDA NADPH oxidase complex
GO:0043410 IEA positive regulation of MAPK cascade
GO:0045726 IMP positive regulation of integrin biosynthetic process
GO:0045730 TAS respiratory burst
GO:0046330 IEA positive regulation of JNK cascade
GO:0046872 IEA metal ion binding
GO:0048365 IPI Rac GTPase binding
GO:0048661 ISS positive regulation of smooth muscle cell proliferation
GO:0050661 IC NADP binding
GO:0051454 IDA intracellular pH elevation
GO:0055114 IDA:IEA oxidation-reduction process
GO:0071438 IDA invadopodium membrane
GO:0071455 IEA cellular response to hyperoxia
GO:0072592 IEA oxygen metabolic process
GO:1902177 IEA positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:1990451 IDA cellular stress response to acidic pH

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033610 Nox1-001 protein_coding Mus_musculus 0 1862
ENSMUST00000159259 Nox1-005 protein_coding Mus_musculus 0 1555
ENSMUST00000113275 Nox1-002 protein_coding Mus_musculus 0 1317

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