C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: histone deacetylase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000373548 HDAC1-001 ENSG00000116478 9606 + 1:32292086-32333635 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000373548
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000373548 16.863±0.00 41.268±0.00 3.140±0.00 3.574±1.66 11.696±4.25 25.085±9.06 6.447±5.71 20.239±17.89 7.697±3.20 11.976±6.88 2.466±0.00 48.877±12.68 31.376±9.31 24.934±16.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008AA CIL_0008AA_0001 VISTA 1:31744429-32345312

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000118 TAS histone deacetylase complex
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000278 TAS mitotic cell cycle
GO:0000785 IDA chromatin
GO:0000790 IDA nuclear chromatin
GO:0000976 ISS transcription regulatory region sequence-specific DNA binding
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001047 IDA core promoter binding
GO:0001103 IPI RNA polymerase II repressing transcription factor binding
GO:0001106 IDA RNA polymerase II transcription corepressor activity
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0004407 TAS:IEA histone deacetylase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005737 TAS cytoplasm
GO:0005829 IDA cytosol
GO:0006338 IC chromatin remodeling
GO:0006351 TAS transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006476 IDA protein deacetylation
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007219 TAS Notch signaling pathway
GO:0007596 TAS blood coagulation
GO:0008134 TAS transcription factor binding
GO:0008284 IMP positive regulation of cell proliferation
GO:0009913 ISS epidermal cell differentiation
GO:0010467 TAS gene expression
GO:0010870 IMP positive regulation of receptor biosynthetic process
GO:0016032 IEA viral process
GO:0016568 TAS chromatin modification
GO:0016575 IMP:IEA histone deacetylation
GO:0016580 IDA Sin3 complex
GO:0016581 IDA NuRD complex
GO:0019213 ISS deacetylase activity
GO:0019899 IPI enzyme binding
GO:0031492 IDA nucleosomal DNA binding
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032922 ISS circadian regulation of gene expression
GO:0033558 IDA protein deacetylase activity
GO:0033613 IPI activating transcription factor binding
GO:0042475 ISS odontogenesis of dentin-containing tooth
GO:0042733 ISS embryonic digit morphogenesis
GO:0042826 IPI histone deacetylase binding
GO:0043044 IDA ATP-dependent chromatin remodeling
GO:0043066 ISS negative regulation of apoptotic process
GO:0043234 IDA protein complex
GO:0043922 IMP negative regulation by host of viral transcription
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045786 TAS negative regulation of cell cycle
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046969 IEA NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 IEA NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0060766 IDA negative regulation of androgen receptor signaling pathway
GO:0060789 ISS hair follicle placode formation
GO:0061029 ISS eyelid development in camera-type eye
GO:0061198 ISS fungiform papilla formation
GO:0070491 IPI repressing transcription factor binding
GO:0070932 IDA histone H3 deacetylation
GO:0070933 IDA histone H4 deacetylation
GO:0097372 IEA NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102597 Hdac1-001 protein_coding Mus_musculus 0 2012
ENSMUST00000079363 Gm10093-201 protein_coding Mus_musculus 0 2004
ENSMUST00000142984 Hdac1-005 retained_intron Mus_musculus 0 676
ENSMUST00000116079 Gm7146-001 processed_pseudogene Mus_musculus 0 512
ENSMUST00000178907 Gm21834-201 protein_coding Mus_musculus 0 510
ENSMUST00000139305 Hdac1-002 retained_intron Mus_musculus 0 473
ENSMUST00000125718 Hdac1-003 retained_intron Mus_musculus 0 394
ENSMUST00000132909 Hdac1-006 retained_intron Mus_musculus 0 307
ENSMUST00000150105 Hdac1-004 retained_intron Mus_musculus 0 303

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