C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: arachidonate 5-lipoxygenase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000374391 ALOX5-001 ENSG00000012779 9606 + 10:45374227-45446115 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374391
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374391 3.705±0.00 14.485±0.00 0.958±0.69 1.725±0.36 0.933±0.20 2.118±0.00 3.427±0.00 1.670±0.63 8.433±0.71 0.035±0.00 2.454±1.17 9.778±1.08 1.092±0.55

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081B CIL_00081B_0001 VISTA 10:45257434-45860222

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002540 IEA leukotriene production involved in inflammatory response
GO:0004051 IDA arachidonate 5-lipoxygenase activity
GO:0005506 IDA iron ion binding
GO:0005515 IPI:IEA protein binding
GO:0005615 IDA extracellular space
GO:0005634 IEA nucleus
GO:0005635 IDA nuclear envelope
GO:0005641 IDA nuclear envelope lumen
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0006691 TAS leukotriene metabolic process
GO:0006954 IEA inflammatory response
GO:0016363 IDA nuclear matrix
GO:0016702 IEA oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0019369 TAS arachidonic acid metabolic process
GO:0019370 IDA leukotriene biosynthetic process
GO:0019372 TAS lipoxygenase pathway
GO:0031965 IDA nuclear membrane
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0055114 IEA oxidation-reduction process
GO:2001300 TAS lipoxin metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000026795 Alox5-001 protein_coding Mus_musculus 0 2403
ENSMUST00000164547 Alox5-004 protein_coding Mus_musculus 0 2039
ENSMUST00000170186 Alox5-005 protein_coding Mus_musculus 0 1624
ENSMUST00000167447 Alox5-002 retained_intron Mus_musculus 0 1622
ENSMUST00000167174 Alox5-006 processed_transcript Mus_musculus 0 676

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