C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: heat shock 70kDa protein 1A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000375651 HSPA1A-001 ENSG00000204389 9606 + 6:31815464-31817946 protein_coding

Homo sapiens EnsemblGRCh38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartLiverMuscleOvaryENST00000375651
Transcript ID Bladder Brain Breast Colon Heart Liver Muscle Ovary
ENST00000375651 4.884±0.00 6.305±0.00 27.603±0.00 9.596±0.00 4.774±0.00 10.022±0.00 12.733±0.00 0.889±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PO CIL_0001PO_0004 CGP 6:31809619-31817946
CIL_0001PO CIL_0001PO_0003 CGP 6:31815464-31830255

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000151 IDA ubiquitin ligase complex
GO:0000902 IEA cell morphogenesis
GO:0001618 IEA virus receptor activity
GO:0001664 IPI G-protein coupled receptor binding
GO:0003725 IDA double-stranded RNA binding
GO:0005515 IPI protein binding
GO:0005524 IDA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 TAS mitochondrion
GO:0005783 TAS endoplasmic reticulum
GO:0005814 IDA centriole
GO:0005829 IDA cytosol
GO:0005925 IDA focal adhesion
GO:0006200 IDA ATP catabolic process
GO:0006402 IDA mRNA catabolic process
GO:0006986 IDA response to unfolded protein
GO:0008180 IDA COP9 signalosome
GO:0008285 IMP negative regulation of cell proliferation
GO:0009615 IEA response to virus
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016234 IDA inclusion body
GO:0016235 IDA aggresome
GO:0016607 IDA nuclear speck
GO:0016887 IDA ATPase activity
GO:0019899 IPI enzyme binding
GO:0030308 IMP negative regulation of cell growth
GO:0030529 IDA ribonucleoprotein complex
GO:0031072 IPI heat shock protein binding
GO:0031397 IDA negative regulation of protein ubiquitination
GO:0031625 IPI ubiquitin protein ligase binding
GO:0031982 IDA vesicle
GO:0034599 TAS cellular response to oxidative stress
GO:0034605 IDA cellular response to heat
GO:0042026 IDA protein refolding
GO:0042623 IDA ATPase activity, coupled
GO:0043066 TAS negative regulation of apoptotic process
GO:0044183 IDA protein binding involved in protein folding
GO:0044822 IDA poly(A) RNA binding
GO:0045648 IMP positive regulation of erythrocyte differentiation
GO:0047485 IPI protein N-terminus binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050821 TAS protein stabilization
GO:0051082 NAS unfolded protein binding
GO:0060548 IDA negative regulation of cell death
GO:0070062 IDA extracellular vesicular exosome
GO:0070370 IMP cellular heat acclimation
GO:0072562 IDA blood microparticle
GO:0090084 IDA negative regulation of inclusion body assembly
GO:2001240 IMP negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000172753 Hspa1b-001 protein_coding Mus_musculus 0 2669
ENSMUST00000087328 Hspa1a-001 protein_coding Mus_musculus 0 2667
ENSMUST00000007248 Hspa1l-001 protein_coding Mus_musculus 0 1725
ENSDART00000010477 hsp70.3-001 protein_coding Danio_rerio 0 1417
ENSDART00000111042 hsp70.2-001 protein_coding Danio_rerio 0 1417
ENSDART00000045767 mcm5-201 protein_coding Danio_rerio 0 1406
ENSDART00000124762 mcm5-001 protein_coding Danio_rerio 0 1406
ENSMUST00000080449 Hspa2-201 protein_coding Mus_musculus 0 1404
ENSDART00000031650 hsp70l-001 protein_coding Danio_rerio 0 1400
ENSDART00000025319 si:ch211-199o1.2-201 protein_coding Danio_rerio 0 1146
ENSDART00000141267 si:ch211-199o1.2-001 protein_coding Danio_rerio 0 1146
ENSDART00000078671 hsp70.2-201 protein_coding Danio_rerio 0 564
ENSDART00000109863 mcm5-202 protein_coding Danio_rerio 0 558
ENSMUST00000173680 Gm20481-001 protein_coding Mus_musculus 0 355

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