C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000379883 DDX58-001 ENSG00000107201 9606 - 9:32455705-32526324 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000379883
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000379883 1.160±0.00 3.109±0.00 1.260±0.00 0.812±0.26 2.748±2.16 2.046±1.58 1.158±0.00 1.739±0.60 1.002±0.31 1.692±0.00 0.658±0.00 2.042±0.51 2.380±0.67 1.504±1.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000437 CIL_000437_0001 CGP 9:32384603-32526324
CIL_00065D CIL_00065D_0001 CGP 9:32455705-32552553

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002230 IMP positive regulation of defense response to virus by host
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0003725 TAS double-stranded RNA binding
GO:0003727 IMP single-stranded RNA binding
GO:0004386 IEA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005923 IDA tight junction
GO:0008152 IEA metabolic process
GO:0008270 IDA zinc ion binding
GO:0009597 IDA detection of virus
GO:0009615 TAS response to virus
GO:0015629 IDA actin cytoskeleton
GO:0016032 IEA viral process
GO:0016787 IEA hydrolase activity
GO:0016817 IEA hydrolase activity, acting on acid anhydrides
GO:0030334 IDA regulation of cell migration
GO:0032480 TAS negative regulation of type I interferon production
GO:0032587 IDA ruffle membrane
GO:0032727 IDA positive regulation of interferon-alpha production
GO:0032728 IDA positive regulation of interferon-beta production
GO:0034344 TAS regulation of type III interferon production
GO:0039528 TAS cytoplasmic pattern recognition receptor signaling pathway in response to virus
GO:0039529 IMP RIG-I signaling pathway
GO:0042802 IPI identical protein binding
GO:0042993 IDA positive regulation of transcription factor import into nucleus
GO:0043330 IEA response to exogenous dsRNA
GO:0045087 IMP innate immune response
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051091 IC positive regulation of sequence-specific DNA binding transcription factor activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000037907 Ddx58-001 protein_coding Mus_musculus 0 2026
ENSMUST00000142055 Ddx58-006 protein_coding Mus_musculus 0 1531
ENSMUST00000137903 Ddx58-005 processed_transcript Mus_musculus 0 1081
ENSMUST00000135966 Ddx58-010 processed_transcript Mus_musculus 0 545

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