C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphodiesterase 4A, cAMP-specific
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000380702 PDE4A-001 ENSG00000065989 9606 + 19:10420655-10469631 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LiverLungOvaryENST00000380702
Transcript ID Liver Lung Ovary
ENST00000380702 0.088±0.00 2.711±0.00 1.112±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004GI CIL_0004GI_0001 CGP 19:10350529-10420121
CIL_00037J CIL_00037J_0001 CGP 19:10391134-10469631
CIL_0004FB CIL_0004FB_0001 CGP 19:10416773-10503741

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004114 IEA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 IDA 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0006198 IEA cAMP catabolic process
GO:0007165 IEA signal transduction
GO:0007608 IEA sensory perception of smell
GO:0010738 IEA regulation of protein kinase A signaling
GO:0016020 TAS membrane
GO:0030552 IGI cAMP binding
GO:0035690 IEA cellular response to drug
GO:0042995 IEA cell projection
GO:0043949 IEA regulation of cAMP-mediated signaling
GO:0046872 IEA metal ion binding
GO:0048471 IDA perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000003395 Pde4a-003 protein_coding Mus_musculus 0 1301
ENSMUST00000115458 Pde4a-002 protein_coding Mus_musculus 0 1301
ENSMUST00000131769 Pde4a-004 retained_intron Mus_musculus 0 1301
ENSMUST00000039413 Pde4a-001 protein_coding Mus_musculus 0 1301
ENSMUST00000110095 Pde4c-001 protein_coding Mus_musculus 0 686
ENSMUST00000128685 Pde4c-004 retained_intron Mus_musculus 0 281
ENSMUST00000140440 Pde4a-005 retained_intron Mus_musculus 0 243

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