C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sirtuin 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000382743 SIRT3-001 ENSG00000142082 9606 - 11:215458-236431 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonHeartKidneyOvaryENST00000382743
Transcript ID Brain Colon Heart Kidney Ovary
ENST00000382743 11.544±0.00 1.272±0.00 6.230±0.00 8.978±0.00 10.319±1.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006LA CIL_0006LA_0001 CGP 11:207511-236931
CIL_0006QN CIL_0006QN_0001 CGP 11:215458-252984

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0006476 IDA:IEA protein deacetylation
GO:0007568 IEA aging
GO:0008270 IDA:IEA zinc ion binding
GO:0009060 IMP aerobic respiration
GO:0016020 IEA membrane
GO:0016811 IEA hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0019899 IEA enzyme binding
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0034983 IMP peptidyl-lysine deacetylation
GO:0051287 IEA NAD binding
GO:0070403 IEA NAD+ binding
GO:0070932 IEA histone H3 deacetylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000106048 Sirt3-002 protein_coding Mus_musculus 0 865
ENSMUST00000026559 Sirt3-001 protein_coding Mus_musculus 0 863
ENSMUST00000147331 Sirt3-004 protein_coding Mus_musculus 0 691
ENSMUST00000137024 Sirt3-005 protein_coding Mus_musculus 0 521
ENSMUST00000137710 Sirt3-003 protein_coding Mus_musculus 0 416

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