C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dual oxidase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000389037 DUOX1-001 ENSG00000137857 9606 + 15:45129994-45165574 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastHeartLiverLungOvaryPlacentaTestisENST00000389037
Transcript ID Brain Breast Heart Liver Lung Ovary Placenta Testis
ENST00000389037 1.456±0.00 0.575±0.00 0.374±0.00 1.128±0.00 6.056±1.13 3.881±0.80 0.747±0.20 3.715±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004DF CIL_0004DF_0001 CGP 15:45114321-45129938
CIL_0004QK CIL_0004QK_0002 CGP 15:45117367-45165576
CIL_0004DG CIL_0004DG_0001 CGP 15:45129933-45201175

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004601 IEA peroxidase activity
GO:0005509 IEA calcium ion binding
GO:0006590 IEA thyroid hormone generation
GO:0006979 IEA response to oxidative stress
GO:0016021 IEA integral component of membrane
GO:0016174 NAS NAD(P)H oxidase activity
GO:0016324 NAS apical plasma membrane
GO:0016491 IEA oxidoreductase activity
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0020037 IEA heme binding
GO:0042335 IMP cuticle development
GO:0042446 IEA hormone biosynthetic process
GO:0042554 NAS superoxide anion generation
GO:0042744 IEA hydrogen peroxide catabolic process
GO:0050661 NAS NADP binding
GO:0050665 NAS hydrogen peroxide biosynthetic process
GO:0051591 ISS response to cAMP
GO:0055114 TAS:IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000099461 Duox1-001 protein_coding Mus_musculus 0 5389
ENSMUST00000053734 Duox2-001 protein_coding Mus_musculus 0 1522
ENSMUST00000155820 Duox2-002 processed_transcript Mus_musculus 0 241

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