C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, metabotropic 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000389335 GRM7-004 ENSG00000196277 9606 + 3:6861240-7693686 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; LungOvaryENST00000389335
Transcript ID Lung Ovary
ENST00000389335 0.055±0.00 0.061±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005RO CIL_0005RO_0001 CGP 3:5187646-7741533
CIL_0003AB CIL_0003AB_0001 CGP 3:6770001-8568125

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001642 IDA group III metabotropic glutamate receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005246 IBA calcium channel regulator activity
GO:0005509 IDA calcium ion binding
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0005938 IDA cell cortex
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007194 IDA negative regulation of adenylate cyclase activity
GO:0007196 IDA adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0007268 IDA synaptic transmission
GO:0007605 IMP sensory perception of sound
GO:0007608 IEA sensory perception of smell
GO:0008066 IDA glutamate receptor activity
GO:0010855 IDA adenylate cyclase inhibitor activity
GO:0014050 ISS negative regulation of glutamate secretion
GO:0016021 IEA:IDA integral component of membrane
GO:0016595 IDA glutamate binding
GO:0030165 NAS PDZ domain binding
GO:0030424 ISS axon
GO:0030425 IDA dendrite
GO:0030818 IDA negative regulation of cAMP biosynthetic process
GO:0031279 IDA regulation of cyclase activity
GO:0032279 ISS asymmetric synapse
GO:0042734 IBA presynaptic membrane
GO:0043198 ISS dendritic shaft
GO:0043235 IDA receptor complex
GO:0045211 ISS postsynaptic membrane
GO:0048786 ISS presynaptic active zone
GO:0051966 IBA regulation of synaptic transmission, glutamatergic
GO:0070905 IDA serine binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000172951 Grm7-001 protein_coding Mus_musculus 0 3812
ENSMUST00000071076 Grm7-003 protein_coding Mus_musculus 0 3812
ENSMUST00000174018 Grm7-002 nonsense_mediated_decay Mus_musculus 0 2916
ENSMUST00000173001 Grm7-004 protein_coding Mus_musculus 0 303
ENSMUST00000174310 Grm7-005 protein_coding Mus_musculus 0 250

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