C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sequestosome 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000389805 SQSTM1-001 ENSG00000161011 9606 + 5:179820759-179838078 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastHeartLiverLungMuscleOvaryPlacentaENST00000389805
Transcript ID Bladder Brain Breast Heart Liver Lung Muscle Ovary Placenta
ENST00000389805 9.241±0.00 14.333±0.00 18.988±0.00 4.631±0.00 17.554±0.00 9.257±0.00 144.284±0.00 23.759±0.00 28.588±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000XE CIL_0000XE_0002 CGP 5:179797597-179838078
CIL_0000XF CIL_0000XF_0002 CGP 5:179806398-179862173

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000407 IEA pre-autophagosomal structure
GO:0000932 IDA cytoplasmic mRNA processing body
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0002376 IEA immune system process
GO:0004674 NAS protein serine/threonine kinase activity
GO:0005080 IPI protein kinase C binding
GO:0005515 IPI:IEA protein binding
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005764 IEA lysosome
GO:0005768 IEA endosome
GO:0005776 IDA autophagic vacuole
GO:0005783 IEA endoplasmic reticulum
GO:0005829 TAS cytosol
GO:0006468 NAS protein phosphorylation
GO:0006511 TAS ubiquitin-dependent protein catabolic process
GO:0006914 IMP autophagy
GO:0006950 TAS response to stress
GO:0008104 TAS protein localization
GO:0008270 IEA zinc ion binding
GO:0016197 TAS endosomal transport
GO:0016234 IDA inclusion body
GO:0016235 IEA aggresome
GO:0016236 ISS macroautophagy
GO:0016239 IMP positive regulation of macroautophagy
GO:0016605 IDA PML body
GO:0019901 IDA protein kinase binding
GO:0030154 IEA cell differentiation
GO:0030971 TAS receptor tyrosine kinase binding
GO:0031410 IEA cytoplasmic vesicle
GO:0035556 TAS intracellular signal transduction
GO:0042169 IDA SH2 domain binding
GO:0042802 IPI identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043065 TAS positive regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0043122 IMP regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043130 IDA ubiquitin binding
GO:0045944 TAS positive regulation of transcription from RNA polymerase II promoter
GO:0046578 NAS regulation of Ras protein signal transduction
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051291 IEA protein heterooligomerization
GO:0070062 IDA extracellular vesicular exosome
GO:0070530 IEA K63-linked polyubiquitin binding
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102774 Sqstm1-001 protein_coding Mus_musculus 0 1459
ENSMUST00000015981 Sqstm1-002 protein_coding Mus_musculus 0 1085
ENSMUST00000143379 Sqstm1-004 protein_coding Mus_musculus 0 970
ENSMUST00000136936 Sqstm1-005 protein_coding Mus_musculus 0 254
ENSMUST00000154805 Sqstm1-006 retained_intron Mus_musculus 0 241

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