C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: thymoma viral proto-oncogene 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000001780 Akt1-001 ENSMUSG00000001729 10090 - 12:112653821-112674276 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001780
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001780 23.587±10.33 56.030±0.00 42.250±14.43 73.339±38.25 12.580±1.96 47.040±15.18 35.218±10.34 10.868±3.83 15.819±10.01 13.496±2.21 18.235±3.83 68.798±45.92 139.539±115.16 4.000±1.60

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001G0 CIL_0001G0_0002 CGP 12:112644828-112674884
CIL_00030T CIL_00030T_0002 CGP 12:112653821-112682747

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000060 IEA protein import into nucleus, translocation
GO:0001649 IGI osteoblast differentiation
GO:0001893 IMP maternal placenta development
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0001938 ISS positive regulation of endothelial cell proliferation
GO:0004672 IDA protein kinase activity
GO:0004674 IDA:ISS protein serine/threonine kinase activity
GO:0004712 ISO protein serine/threonine/tyrosine kinase activity
GO:0005080 IEA protein kinase C binding
GO:0005515 IPI protein binding
GO:0005547 IEA phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005819 IDA spindle
GO:0005829 TAS cytosol
GO:0005886 ISO plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005977 IMP glycogen metabolic process
GO:0005978 IEA glycogen biosynthetic process
GO:0005979 IEA regulation of glycogen biosynthetic process
GO:0006006 IMP glucose metabolic process
GO:0006412 IEA translation
GO:0006417 IEA regulation of translation
GO:0006468 IDA protein phosphorylation
GO:0006469 IEA negative regulation of protein kinase activity
GO:0006924 ISO activation-induced cell death of T cells
GO:0006954 IDA inflammatory response
GO:0006979 ISS response to oxidative stress
GO:0007010 TAS cytoskeleton organization
GO:0007165 IEA signal transduction
GO:0007281 IDA germ cell development
GO:0007568 IEA aging
GO:0008286 ISS insulin receptor signaling pathway
GO:0008637 IDA apoptotic mitochondrial changes
GO:0009725 IDA response to hormone
GO:0010507 IEA negative regulation of autophagy
GO:0010748 IEA negative regulation of plasma membrane long-chain fatty acid transport
GO:0010765 IDA positive regulation of sodium ion transport
GO:0010907 IEA positive regulation of glucose metabolic process
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0010975 IDA regulation of neuron projection development
GO:0015630 IEA microtubule cytoskeleton
GO:0015758 IMP glucose transport
GO:0016301 ISO kinase activity
GO:0016310 IEA phosphorylation
GO:0016567 IDA protein ubiquitination
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0019899 IEA enzyme binding
GO:0019901 IPI protein kinase binding
GO:0030030 ISO cell projection organization
GO:0030163 IDA protein catabolic process
GO:0030212 IEA hyaluronan metabolic process
GO:0030235 IEA nitric-oxide synthase regulator activity
GO:0030307 IEA positive regulation of cell growth
GO:0030334 ISS regulation of cell migration
GO:0031018 TAS endocrine pancreas development
GO:0031641 IMP regulation of myelination
GO:0031659 IEA positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
GO:0031999 IEA negative regulation of fatty acid beta-oxidation
GO:0032094 IDA response to food
GO:0032270 IEA positive regulation of cellular protein metabolic process
GO:0032287 IMP peripheral nervous system myelin maintenance
GO:0032436 IMP positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032869 IDA cellular response to insulin stimulus
GO:0032880 IDA regulation of protein localization
GO:0033138 IEA positive regulation of peptidyl-serine phosphorylation
GO:0034405 IEA response to fluid shear stress
GO:0035556 ISO intracellular signal transduction
GO:0036064 IDA ciliary basal body
GO:0042593 IMP glucose homeostasis
GO:0042802 IEA identical protein binding
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043325 IEA phosphatidylinositol-3,4-bisphosphate binding
GO:0043491 IGI protein kinase B signaling
GO:0043536 IEA positive regulation of blood vessel endothelial cell migration
GO:0045429 IEA positive regulation of nitric oxide biosynthetic process
GO:0045600 IEA positive regulation of fat cell differentiation
GO:0045725 IEA positive regulation of glycogen biosynthetic process
GO:0045792 ISO negative regulation of cell size
GO:0045861 IEA negative regulation of proteolysis
GO:0045907 IEA positive regulation of vasoconstriction
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046326 IEA positive regulation of glucose import
GO:0046329 IEA negative regulation of JNK cascade
GO:0046889 IEA positive regulation of lipid biosynthetic process
GO:0048009 ISS insulin-like growth factor receptor signaling pathway
GO:0051000 IEA positive regulation of nitric-oxide synthase activity
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051146 IGI striated muscle cell differentiation
GO:0060709 IMP glycogen cell differentiation involved in embryonic placenta development
GO:0060716 IMP labyrinthine layer blood vessel development
GO:0070141 IEA response to UV-A
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071363 IDA cellular response to growth factor stimulus
GO:0071364 IDA cellular response to epidermal growth factor stimulus
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071456 IEA cellular response to hypoxia
GO:0071889 IEA 14-3-3 protein binding
GO:0090004 IEA positive regulation of establishment of protein localization to plasma membrane
GO:0090201 IDA negative regulation of release of cytochrome c from mitochondria
GO:0097011 IDA cellular response to granulocyte macrophage colony-stimulating factor stimulus
GO:0097194 IDA execution phase of apoptosis
GO:1901653 IDA cellular response to peptide

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000130716 CABZ01115725.1-201 protein_coding Danio_rerio 0 219
ENST00000311278 AKT2-027 protein_coding Homo_sapiens 0 401
ENST00000349310 AKT1-001 protein_coding Homo_sapiens 0 1958
ENST00000391844 AKT2-026 nonsense_mediated_decay Homo_sapiens 0 950
ENST00000391845 AKT2-017 processed_transcript Homo_sapiens 0 612
ENST00000392038 AKT2-001 protein_coding Homo_sapiens 0 965
ENST00000402615 AKT1-003 protein_coding Homo_sapiens 0 1958
ENST00000407796 AKT1-002 protein_coding Homo_sapiens 0 2069
ENST00000424901 AKT2-201 protein_coding Homo_sapiens 0 401
ENST00000476247 AKT2-041 protein_coding Homo_sapiens 0 305
ENST00000476266 AKT2-002 retained_intron Homo_sapiens 0 843
ENST00000483166 AKT2-003 retained_intron Homo_sapiens 0 523
ENST00000489375 AKT2-019 nonsense_mediated_decay Homo_sapiens 9.99995e-41 171
ENST00000496089 AKT2-022 retained_intron Homo_sapiens 0 403
ENST00000544168 AKT1-007 protein_coding Homo_sapiens 0 1735
ENST00000553506 AKT1-009 retained_intron Homo_sapiens 0 1035
ENST00000554192 AKT1-010 protein_coding Homo_sapiens 0 503
ENST00000554581 AKT1-005 protein_coding Homo_sapiens 0 1958
ENST00000554585 AKT1-017 nonsense_mediated_decay Homo_sapiens 0 588
ENST00000554826 AKT1-016 retained_intron Homo_sapiens 0 604
ENST00000554848 AKT1-004 protein_coding Homo_sapiens 0 1947
ENST00000555380 AKT1-013 protein_coding Homo_sapiens 0 586
ENST00000555458 AKT1-018 protein_coding Homo_sapiens 0 619
ENST00000555528 AKT1-006 protein_coding Homo_sapiens 0 1958
ENST00000555926 AKT1-014 protein_coding Homo_sapiens 0 355
ENST00000556836 AKT1-015 retained_intron Homo_sapiens 0 267
ENST00000557552 AKT1-008 retained_intron Homo_sapiens 0 409
ENST00000578615 AKT2-035 protein_coding Homo_sapiens 0 647
ENST00000579047 AKT2-025 protein_coding Homo_sapiens 0 922
ENST00000584288 AKT2-024 nonsense_mediated_decay Homo_sapiens 0 952

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