Transcript Info |
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Description: | pyruvate dehydrogenase kinase, isozyme 1 | |||||
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Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
ENST00000392571 | PDK1-003 | ENSG00000152256 | 9606 | + | 2:172556007-172595969 | protein_coding |
Expression PatternsNo expression data. |
Conserved Regions | |||
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Region ID | Sub-Region | Region Type | Position |
CIL_0004K8 | CIL_0004K8_0001 | CGP | 2:172427354-172608669 |
CIL_0004KA | CIL_0004KA_0001 | CGP | 2:172555373-173052893 |
Gene Ontology | ||
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GO ID | Evidence Type | GO Description |
GO:0004672 | IDA | protein kinase activity |
GO:0004674 | IEA | protein serine/threonine kinase activity |
GO:0004740 | IMP | pyruvate dehydrogenase (acetyl-transferring) kinase activity |
GO:0005515 | IPI | protein binding |
GO:0005524 | IEA | ATP binding |
GO:0005739 | TAS | mitochondrion |
GO:0005759 | TAS | mitochondrial matrix |
GO:0005967 | IEA | mitochondrial pyruvate dehydrogenase complex |
GO:0006006 | IEA | glucose metabolic process |
GO:0006090 | TAS | pyruvate metabolic process |
GO:0006468 | IEA | protein phosphorylation |
GO:0008283 | IMP | cell proliferation |
GO:0008631 | IMP | intrinsic apoptotic signaling pathway in response to oxidative stress |
GO:0010510 | TAS | regulation of acetyl-CoA biosynthetic process from pyruvate |
GO:0010906 | IMP | regulation of glucose metabolic process |
GO:0044237 | TAS | cellular metabolic process |
GO:0044281 | TAS | small molecule metabolic process |
GO:0097411 | IMP | hypoxia-inducible factor-1alpha signaling pathway |
Homologs | |||||
ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
ENSMUST00000006669 | Pdk1-001 | protein_coding | Mus_musculus | 0 | 1062 |
ENSMUST00000152696 | Pdk1-004 | processed_transcript | Mus_musculus | 0 | 697 |
ENSMUST00000151358 | Pdk1-003 | processed_transcript | Mus_musculus | 0 | 632 |
ENSMUST00000134362 | Pdk1-007 | processed_transcript | Mus_musculus | 0 | 462 |
ENSMUST00000156036 | Pdk1-002 | processed_transcript | Mus_musculus | 0 | 462 |
ENSMUST00000148249 | Pdk1-006 | processed_transcript | Mus_musculus | 0 | 357 |
ENSMUST00000129887 | Pdk1-005 | processed_transcript | Mus_musculus | 0 | 274 |
ENSMUST00000129427 | Pdk1-008 | processed_transcript | Mus_musculus | 0 | 265 |