C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: suppressor of cytokine signaling 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000394861 SOCS5-002 ENSG00000171150 9606 + 2:46699187-46762313 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000394861
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000394861 2.931±0.00 2.772±0.00 0.956±0.00 3.657±0.62 2.440±0.40 3.250±0.10 1.765±0.34 1.009±0.08 2.409±1.74 2.030±0.37 1.483±0.39 3.727±0.89 1.774±0.57 3.987±1.91

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006KQ CIL_0006KQ_0001 CGP 2:46616416-46763129
CIL_0006KK CIL_0006KK_0001 CGP 2:46698952-46941855

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0007175 IDA negative regulation of epidermal growth factor-activated receptor activity
GO:0007259 IEA JAK-STAT cascade
GO:0009968 NAS negative regulation of signal transduction
GO:0016049 NAS cell growth
GO:0016567 IEA protein ubiquitination
GO:0019221 ISS cytokine-mediated signaling pathway
GO:0030971 IPI receptor tyrosine kinase binding
GO:0032436 IMP positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556 IEA intracellular signal transduction
GO:0040008 IEA regulation of growth
GO:0045627 ISS positive regulation of T-helper 1 cell differentiation
GO:0045629 ISS negative regulation of T-helper 2 cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000041369 Socs5-201 protein_coding Mus_musculus 0 1897

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