C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000394904 SLC11A2-201 ENSG00000110911 9606 - 12:50985992-51028275 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007B4 CIL_0007B4_0001 CGP 12:50953922-51028566

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000041 IEA transition metal ion transport
GO:0001666 IEP response to hypoxia
GO:0003032 IEP detection of oxygen
GO:0005215 IEA transporter activity
GO:0005375 IDA copper ion transmembrane transporter activity
GO:0005381 IEA iron ion transmembrane transporter activity
GO:0005384 IDA manganese ion transmembrane transporter activity
GO:0005385 IDA zinc ion transmembrane transporter activity
GO:0005506 IEA iron ion binding
GO:0005507 IEA copper ion binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005764 IDA lysosome
GO:0005765 IDA lysosomal membrane
GO:0005768 IEA endosome
GO:0005769 IDA early endosome
GO:0005770 IDA late endosome
GO:0005773 IMP vacuole
GO:0005802 IDA trans-Golgi network
GO:0005886 IMP plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0005903 IEA brush border
GO:0006778 IEA porphyrin-containing compound metabolic process
GO:0006779 IEA porphyrin-containing compound biosynthetic process
GO:0006783 IEA heme biosynthetic process
GO:0006810 IEA transport
GO:0006824 IDA cobalt ion transport
GO:0006825 IDA copper ion transport
GO:0006826 IEA iron ion transport
GO:0006828 IDA manganese ion transport
GO:0006878 IEA cellular copper ion homeostasis
GO:0006879 TAS cellular iron ion homeostasis
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007611 IEA learning or memory
GO:0008270 IEA zinc ion binding
GO:0009986 IDA cell surface
GO:0010039 IEP response to iron ion
GO:0010042 IEA response to manganese ion
GO:0010288 IEA response to lead ion
GO:0012505 IEA endomembrane system
GO:0015078 IEA hydrogen ion transmembrane transporter activity
GO:0015086 IDA cadmium ion transmembrane transporter activity
GO:0015087 IDA cobalt ion transmembrane transporter activity
GO:0015093 IDA ferrous iron transmembrane transporter activity
GO:0015094 IDA lead ion transmembrane transporter activity
GO:0015099 IDA nickel cation transmembrane transporter activity
GO:0015100 IDA vanadium ion transmembrane transporter activity
GO:0015295 IDA solute:proton symporter activity
GO:0015675 IDA nickel cation transport
GO:0015676 IDA vanadium ion transport
GO:0015684 IDA ferrous iron transport
GO:0015692 IDA lead ion transport
GO:0015992 IEA proton transport
GO:0016020 IDA:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016151 IEA nickel cation binding
GO:0016324 IDA apical plasma membrane
GO:0022890 IGI inorganic cation transmembrane transporter activity
GO:0030145 IEA manganese ion binding
GO:0031410 IDA cytoplasmic vesicle
GO:0031902 IDA late endosome membrane
GO:0034599 IDA cellular response to oxidative stress
GO:0035444 IDA nickel cation transmembrane transport
GO:0045177 IDA apical part of cell
GO:0045178 IDA basal part of cell
GO:0046686 IEA response to cadmium ion
GO:0046870 IEA cadmium ion binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048813 IEA dendrite morphogenesis
GO:0048821 IEA erythrocyte development
GO:0050897 IEA cobalt ion binding
GO:0055037 IDA recycling endosome
GO:0055085 TAS transmembrane transport
GO:0060586 IMP multicellular organismal iron ion homeostasis
GO:0070574 IDA cadmium ion transmembrane transport
GO:0070627 IDA ferrous iron import
GO:0070826 IDA paraferritin complex
GO:0071281 IEA cellular response to iron ion
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071421 IDA manganese ion transmembrane transport
GO:0071456 IEA cellular response to hypoxia
GO:0071577 IDA zinc ion transmembrane transport
GO:0098655 IGI cation transmembrane transport
GO:1902600 IEA hydrogen ion transmembrane transport
GO:1902861 IEA copper ion import into cell

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000138843 Slc11a2-002 protein_coding Mus_musculus 0 2178
ENSMUST00000023774 Slc11a2-001 protein_coding Mus_musculus 0 1975
ENSMUST00000124324 Slc11a2-009 protein_coding Mus_musculus 0 817
ENSMUST00000140535 Slc11a2-008 retained_intron Mus_musculus 0 784
ENSMUST00000123461 Slc11a2-005 protein_coding Mus_musculus 0 601
ENSMUST00000136168 Slc11a2-004 nonsense_mediated_decay Mus_musculus 0 377
ENSMUST00000154331 Slc11a2-003 protein_coding Mus_musculus 0 298

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