C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein phosphatase, Mg2+/Mn2+ dependent, 1A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000395076 PPM1A-001 ENSG00000100614 9606 + 14:60249268-60299087 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000395076
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000395076 4.070±0.00 1.797±0.00 3.517±0.00 10.444±0.82 3.970±0.45 6.652±0.13 5.494±0.33 4.848±1.63 4.468±2.83 4.581±2.01 9.680±5.37 2.790±0.27 1.774±0.95 4.356±0.31

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00036H CIL_00036H_0002 CGP 14:60144120-60299087
CIL_0000S6 CIL_0000S6_0001 CGP 14:60245752-60515543

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0000287 IEA magnesium ion binding
GO:0003824 IEA catalytic activity
GO:0004721 IEA phosphoprotein phosphatase activity
GO:0004722 IEA:IDA protein serine/threonine phosphatase activity
GO:0004871 IMP signal transducer activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 ISS cytosol
GO:0006351 TAS transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006470 IMP protein dephosphorylation
GO:0006499 ISS N-terminal protein myristoylation
GO:0007050 TAS cell cycle arrest
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0008286 TAS insulin receptor signaling pathway
GO:0010467 TAS gene expression
GO:0010991 IDA negative regulation of SMAD protein complex assembly
GO:0016020 ISS membrane
GO:0016055 IDA Wnt signaling pathway
GO:0016311 IDA dephosphorylation
GO:0030145 IEA manganese ion binding
GO:0030177 IDA positive regulation of Wnt signaling pathway
GO:0030512 IDA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0033192 IDA calmodulin-dependent protein phosphatase activity
GO:0035970 IDA peptidyl-threonine dephosphorylation
GO:0042347 IMP negative regulation of NF-kappaB import into nucleus
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043124 IMP negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0070412 IPI R-SMAD binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021514 Ppm1a-201 protein_coding Mus_musculus 0 2364
ENSMUST00000173237 Gm6004-001 processed_pseudogene Mus_musculus 0 1127
ENSMUST00000172692 Gm7211-001 processed_pseudogene Mus_musculus 0 1079

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