C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: chemokine (C-X-C motif) ligand 12
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000395794 CXCL12-004 ENSG00000107562 9606 - 10:44377164-44385049 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007QA CIL_0007QA_0001 VISTA 10:43961287-44562544

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001569 IEA patterning of blood vessels
GO:0001666 IEA response to hypoxia
GO:0001667 IEA ameboidal cell migration
GO:0001764 IEA neuron migration
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0005102 TAS receptor binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0005886 IEA plasma membrane
GO:0006874 TAS cellular calcium ion homeostasis
GO:0006935 TAS chemotaxis
GO:0006955 IEA immune response
GO:0007155 TAS cell adhesion
GO:0007165 TAS signal transduction
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007281 IEA germ cell development
GO:0007420 IEA brain development
GO:0008009 TAS:IEA chemokine activity
GO:0008015 TAS blood circulation
GO:0008045 IEA motor neuron axon guidance
GO:0008064 TAS regulation of actin polymerization or depolymerization
GO:0008083 IEA growth factor activity
GO:0008284 IEA positive regulation of cell proliferation
GO:0008344 IEA adult locomotory behavior
GO:0008354 IEA germ cell migration
GO:0009314 IEA response to radiation
GO:0009408 IEA response to heat
GO:0009612 IEA response to mechanical stimulus
GO:0009615 TAS response to virus
GO:0009897 IEA external side of plasma membrane
GO:0022029 IEA telencephalon cell migration
GO:0030334 IEA regulation of cell migration
GO:0030335 IEA positive regulation of cell migration
GO:0031100 IEA organ regeneration
GO:0033603 IEA positive regulation of dopamine secretion
GO:0042098 IEA T cell proliferation
GO:0042379 IMP chemokine receptor binding
GO:0043434 IEA response to peptide hormone
GO:0045236 IDA CXCR chemokine receptor binding
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045785 IDA positive regulation of cell adhesion
GO:0048842 IEA positive regulation of axon extension involved in axon guidance
GO:0050930 IEA induction of positive chemotaxis
GO:0051924 IEA regulation of calcium ion transport
GO:0060326 IDA cell chemotaxis
GO:0070062 IDA extracellular vesicular exosome
GO:0070098 IDA chemokine-mediated signaling pathway
GO:0090026 IDA positive regulation of monocyte chemotaxis
GO:0090280 TAS positive regulation of calcium ion import
GO:1901741 IEA positive regulation of myoblast fusion
GO:1902230 IDA negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1903237 IDA negative regulation of leukocyte tethering or rolling
GO:2000107 IDA negative regulation of leukocyte apoptotic process
GO:2000406 IDA positive regulation of T cell migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000134244 Cxcl12-004 retained_intron Mus_musculus 0 370
ENSMUST00000073043 Cxcl12-003 protein_coding Mus_musculus 0 370
ENSMUST00000112871 Cxcl12-002 protein_coding Mus_musculus 0 370
ENSMUST00000112866 Cxcl12-001 protein_coding Mus_musculus 0 370

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