C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: chemokine (C-X-C motif) ligand 12
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000112871 Cxcl12-002 ENSMUSG00000061353 10090 + 6:117168574-117181366 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastKidneyLiverOvaryPlacentaTestisENSMUST00000112871
Transcript ID Brain Breast Kidney Liver Ovary Placenta Testis
ENSMUST00000112871 4.754±2.91 11.602±0.00 43.879±4.07 43.232±27.03 13.435±8.52 3.956±2.79 1.245±0.32

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00055S CIL_00055S_0002 CGP 6:116692630-117181367
CIL_0007QA CIL_0007QA_0002 VISTA 6:116979209-117580409

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001569 IMP patterning of blood vessels
GO:0001667 IMP ameboidal cell migration
GO:0005615 IEA extracellular space
GO:0006955 IEA immune response
GO:0007281 IDA germ cell development
GO:0007420 IDA brain development
GO:0008009 IDA chemokine activity
GO:0008045 IMP motor neuron axon guidance
GO:0008083 IEA growth factor activity
GO:0008354 IDA germ cell migration
GO:0009897 IDA external side of plasma membrane
GO:0030334 IDA regulation of cell migration
GO:0030335 IDA positive regulation of cell migration
GO:0042098 IMP T cell proliferation
GO:0042379 ISS chemokine receptor binding
GO:0045785 ISO positive regulation of cell adhesion
GO:0050930 IDA induction of positive chemotaxis
GO:0060326 IEA cell chemotaxis
GO:1901741 IMP positive regulation of myoblast fusion
GO:2000406 ISO positive regulation of T cell migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000343575 CXCL12-001 protein_coding Homo_sapiens 0 372
ENST00000374426 CXCL12-003 protein_coding Homo_sapiens 0 374
ENST00000374429 CXCL12-002 protein_coding Homo_sapiens 0 490
ENST00000395794 CXCL12-004 protein_coding Homo_sapiens 0 370
ENST00000488591 CXCL12-007 retained_intron Homo_sapiens 0 243
ENST00000496375 CXCL12-006 processed_transcript Homo_sapiens 0 283

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