C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear factor, erythroid 2-like 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000397062 NFE2L2-001 ENSG00000116044 9606 - 2:177230305-177265131 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000397062
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000397062 15.151±0.00 11.877±0.00 4.626±0.00 10.934±0.00 4.474±0.00 13.006±0.00 18.022±11.26 10.055±5.42 17.280±12.95 3.825±1.78 23.486±17.53 15.465±6.34 21.092±4.40

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00017P CIL_00017P_0001 CGP 2:177212563-177392697
CIL_00017Q CIL_00017Q_0001 CGP 2:177227595-177543836

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000785 IEA chromatin
GO:0000976 TAS transcription regulatory region sequence-specific DNA binding
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001205 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001221 IEA transcription cofactor binding
GO:0003677 IDA:IEA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0010499 IDA proteasomal ubiquitin-independent protein catabolic process
GO:0010628 IGI positive regulation of gene expression
GO:0016567 IDA protein ubiquitination
GO:0019904 IPI protein domain specific binding
GO:0030194 IEA positive regulation of blood coagulation
GO:0030968 IEA endoplasmic reticulum unfolded protein response
GO:0034599 IEA cellular response to oxidative stress
GO:0036003 IMP positive regulation of transcription from RNA polymerase II promoter in response to stress
GO:0036091 IEA positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 TAS transcription regulatory region DNA binding
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0045995 IEA regulation of embryonic development
GO:0060548 IEA negative regulation of cell death
GO:0070301 IMP cellular response to hydrogen peroxide
GO:0071356 IMP cellular response to tumor necrosis factor
GO:0071499 IMP cellular response to laminar fluid shear stress
GO:1902176 IMP negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:1903206 IGI negative regulation of hydrogen peroxide-induced cell death
GO:2000121 IEA regulation of removal of superoxide radicals
GO:2000352 IMP negative regulation of endothelial cell apoptotic process
GO:2000379 IEA positive regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102672 Nfe2l2-001 protein_coding Mus_musculus 0 1858

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