C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear factor, erythroid 2-like 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000397063 NFE2L2-002 ENSG00000116044 9606 - 2:177230305-177263800 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungOvaryTestisENST00000397063
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Ovary Testis
ENST00000397063 11.019±0.00 6.657±1.58 3.461±0.00 3.922±0.00 3.945±0.00 16.002±0.00 5.704±0.00 11.191±0.00 17.034±6.38 12.108±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00017P CIL_00017P_0001 CGP 2:177212563-177392697
CIL_00017Q CIL_00017Q_0001 CGP 2:177227595-177543836

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000976 TAS transcription regulatory region sequence-specific DNA binding
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0003677 IDA:IEA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0010499 IDA proteasomal ubiquitin-independent protein catabolic process
GO:0010628 IGI positive regulation of gene expression
GO:0016567 IDA protein ubiquitination
GO:0019904 IPI protein domain specific binding
GO:0036003 IMP positive regulation of transcription from RNA polymerase II promoter in response to stress
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 TAS transcription regulatory region DNA binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0070301 IMP cellular response to hydrogen peroxide
GO:0071356 IMP cellular response to tumor necrosis factor
GO:0071499 IMP cellular response to laminar fluid shear stress
GO:1902176 IMP negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:1903206 IGI negative regulation of hydrogen peroxide-induced cell death
GO:2000352 IMP negative regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102672 Nfe2l2-001 protein_coding Mus_musculus 0 1779

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