| Transcript ID | Adrenal | Bladder | Brain | Breast | Colon | Heart | Kidney | Liver | Lung | Muscle | Ovary | Placenta |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ENST00000397843 | 2.911±0.00 | 11.924±0.00 | 6.803±1.80 | 4.594±2.69 | 4.013±0.00 | 1.984±0.00 | 4.634±1.21 | 6.452±0.00 | 3.974±0.70 | 1.430±0.61 | 2.962±1.11 | 1.571±0.14 |
Transcript Info |
||||||
| Description: | Rho guanine nucleotide exchange factor (GEF) 12 | |||||
|---|---|---|---|---|---|---|
| Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
|
ENST00000397843 |
ARHGEF12-001 |
ENSG00000196914 |
9606 | + |
11:120337078-120489936 |
protein_coding |
Expression Patterns
|
Conserved Regions | |||
|---|---|---|---|
| Region ID | Sub-Region | Region Type | Position |
| CIL_00021Z | CIL_00021Z_0002 | CGP | 11:120325129-120489936 |
Gene Ontology | ||
|---|---|---|
| GO ID | Evidence Type | GO Description |
| GO:0001664 | IDA | G-protein coupled receptor binding |
| GO:0005089 | IEA | Rho guanyl-nucleotide exchange factor activity |
| GO:0005096 | IEA | GTPase activator activity |
| GO:0005515 | IPI:IEA | protein binding |
| GO:0005737 | IEA:IDA | cytoplasm |
| GO:0005829 | TAS | cytosol |
| GO:0007186 | IDA | G-protein coupled receptor signaling pathway |
| GO:0007264 | TAS | small GTPase mediated signal transduction |
| GO:0007411 | TAS | axon guidance |
| GO:0016020 | IEA | membrane |
| GO:0032321 | IEA | positive regulation of Rho GTPase activity |
| GO:0035023 | IEA | regulation of Rho protein signal transduction |
| GO:0035556 | IEA | intracellular signal transduction |
| GO:0038032 | IEA | termination of G-protein coupled receptor signaling pathway |
| GO:0043065 | TAS | positive regulation of apoptotic process |
| GO:0048011 | TAS | neurotrophin TRK receptor signaling pathway |
| GO:0051056 | TAS | regulation of small GTPase mediated signal transduction |
| GO:0070062 | IDA | extracellular vesicular exosome |
| GO:0097190 | TAS | apoptotic signaling pathway |
Homologs | |||||
| ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
|
ENSMUST00000165665
|
Arhgef12-202 | protein_coding | Mus_musculus | 0 | 6527 |
|
ENSMUST00000072767
|
Arhgef12-201 | protein_coding | Mus_musculus | 0 | 6239 |