C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho guanine nucleotide exchange factor (GEF) 12
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000397843 ARHGEF12-001 ENSG00000196914 9606 + 11:120337078-120489936 protein_coding

Homo sapiens EnsemblGRCh38

Genome
Exciting message
Genes
Structures from Ensembl
Connecting
Transcripts
Structures from Ensembl
Connecting
Powered by Dalliance 0.11.11

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000397843
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000397843 2.911±0.00 11.924±0.00 6.803±1.80 4.594±2.69 4.013±0.00 1.984±0.00 4.634±1.21 6.452±0.00 3.974±0.70 1.430±0.61 2.962±1.11 1.571±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00021Z CIL_00021Z_0002 CGP 11:120325129-120489936

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001664 IDA G-protein coupled receptor binding
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005096 IEA GTPase activator activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA:IDA cytoplasm
GO:0005829 TAS cytosol
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007411 TAS axon guidance
GO:0016020 IEA membrane
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043065 TAS positive regulation of apoptotic process
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0070062 IDA extracellular vesicular exosome
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000165665 Arhgef12-202 protein_coding Mus_musculus 0 6527
ENSMUST00000072767 Arhgef12-201 protein_coding Mus_musculus 0 6239

Loading