C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho guanine nucleotide exchange factor (GEF) 12
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000165665 Arhgef12-202 ENSMUSG00000059495 10090 - 9:42963842-43105718 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000165665
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000165665 8.120±1.64 7.042±1.36 6.405±2.36 5.017±1.78 4.436±0.66 2.356±0.35 12.879±1.07 16.571±2.26 4.843±2.41 18.814±5.32 3.220±1.56 6.898±1.82 5.729±2.73 2.882±0.52

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003MJ CIL_0003MJ_0002 CGP 9:42963842-43116570

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001664 IEA G-protein coupled receptor binding
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005737 IEA cytoplasm
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000243810 SP140L-201 protein_coding Homo_sapiens 0 420
ENST00000343805 SP140-009 protein_coding Homo_sapiens 0 436
ENST00000356641 ARHGEF12-015 protein_coding Homo_sapiens 0 5954
ENST00000392045 SP140-002 protein_coding Homo_sapiens 0 436
ENST00000396563 SP140L-202 protein_coding Homo_sapiens 0 396
ENST00000397843 ARHGEF12-001 protein_coding Homo_sapiens 0 6527
ENST00000415673 SP140L-009 protein_coding Homo_sapiens 0 420
ENST00000417495 SP140-004 protein_coding Homo_sapiens 0 436
ENST00000420434 SP140-201 protein_coding Homo_sapiens 0 436
ENST00000479539 SP140-005 retained_intron Homo_sapiens 3e-30 135
ENST00000483728 SP140L-002 retained_intron Homo_sapiens 0 239
ENST00000497212 SP140L-007 retained_intron Homo_sapiens 5e-35 152
ENST00000525222 ARHGEF12-012 retained_intron Homo_sapiens 0 627
ENST00000528225 ARHGEF12-008 retained_intron Homo_sapiens 0 1120
ENST00000529970 ARHGEF12-006 retained_intron Homo_sapiens 0 4205
ENST00000530388 ARHGEF12-005 retained_intron Homo_sapiens 2.99878e-43 182
ENST00000530747 ARHGEF12-013 retained_intron Homo_sapiens 0 573
ENST00000531616 ARHGEF12-010 retained_intron Homo_sapiens 0 545
ENST00000532823 ARHGEF12-011 retained_intron Homo_sapiens 0 527
ENST00000532993 ARHGEF12-003 protein_coding Homo_sapiens 0 6233
ENST00000612968 ARHGEF12-016 retained_intron Homo_sapiens 0 407

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