C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000397850 ITGB2-002 ENSG00000160255 9606 - 21:44885953-44928873 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001948 IPI glycoprotein binding
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002523 IEA leukocyte migration involved in inflammatory response
GO:0004872 IEA receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0006915 NAS apoptotic process
GO:0006954 NAS inflammatory response
GO:0007155 TAS cell adhesion
GO:0007159 IDA leukocyte cell-cell adhesion
GO:0007160 IEA:IMP cell-matrix adhesion
GO:0007229 IEA:NAS integrin-mediated signaling pathway
GO:0007267 NAS cell-cell signaling
GO:0007275 IEA multicellular organismal development
GO:0007568 IEA aging
GO:0007596 TAS blood coagulation
GO:0008305 IEA:NAS integrin complex
GO:0008360 NAS regulation of cell shape
GO:0009986 IDA cell surface
GO:0016020 IDA:IEA membrane
GO:0016337 IEA single organismal cell-cell adhesion
GO:0019901 IPI protein kinase binding
GO:0030101 IEA natural killer cell activation
GO:0030198 TAS extracellular matrix organization
GO:0030369 IMP ICAM-3 receptor activity
GO:0030593 IDA neutrophil chemotaxis
GO:0031982 IDA vesicle
GO:0032403 IEA protein complex binding
GO:0034113 IMP heterotypic cell-cell adhesion
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034687 IDA integrin alphaL-beta2 complex
GO:0035987 IEP endodermal cell differentiation
GO:0043113 IMP receptor clustering
GO:0043235 IDA receptor complex
GO:0043542 IEA endothelial cell migration
GO:0045087 TAS innate immune response
GO:0045121 IEA membrane raft
GO:0045123 IEA cellular extravasation
GO:0045429 IEA positive regulation of nitric oxide biosynthetic process
GO:0045766 IEA positive regulation of angiogenesis
GO:0046872 IEA metal ion binding
GO:0046982 IEA protein heterodimerization activity
GO:0050730 IDA regulation of peptidyl-tyrosine phosphorylation
GO:0050776 TAS regulation of immune response
GO:0050798 IEA activated T cell proliferation
GO:0050839 IMP cell adhesion molecule binding
GO:0050900 TAS leukocyte migration
GO:0051092 IEA positive regulation of NF-kappaB transcription factor activity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000000299 Itgb2-001 protein_coding Mus_musculus 0 1844
ENSMUST00000153541 Itgb2-003 nonsense_mediated_decay Mus_musculus 0 1299
ENSMUST00000156644 Itgb2-002 nonsense_mediated_decay Mus_musculus 0 1044
ENSMUST00000113773 Itgb2l-002 protein_coding Mus_musculus 0 630
ENSMUST00000000161 Itgb2l-001 protein_coding Mus_musculus 0 630
ENSMUST00000131567 Itgb2l-003 nonsense_mediated_decay Mus_musculus 0 628
ENSMUST00000130059 Itgb2-005 protein_coding Mus_musculus 0 431
ENSMUST00000131777 Itgb2l-004 processed_transcript Mus_musculus 0 425

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