C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin beta 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000000299 Itgb2-001 ENSMUSG00000000290 10090 + 10:77530252-77565686 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000299
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000299 6.924±1.71 2.860±0.60 6.072±0.57 0.969±1.04 23.257±5.11 4.210±0.73 2.389±1.05 3.280±1.70 6.246±5.22 37.648±0.81 0.496±0.54 6.498±1.20 1.635±1.07 0.245±0.14

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001948 IEA glycoprotein binding
GO:0002523 IEA leukocyte migration involved in inflammatory response
GO:0004872 IEA receptor activity
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0007155 IMP cell adhesion
GO:0007159 IEA leukocyte cell-cell adhesion
GO:0007160 IEA cell-matrix adhesion
GO:0007229 IDA integrin-mediated signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0007568 IEA aging
GO:0008305 IEA integrin complex
GO:0009986 IDA cell surface
GO:0016020 IDA membrane
GO:0016337 IGI single organismal cell-cell adhesion
GO:0019901 IEA protein kinase binding
GO:0030101 IEA natural killer cell activation
GO:0030369 IEA ICAM-3 receptor activity
GO:0030593 IMP neutrophil chemotaxis
GO:0031982 IEA vesicle
GO:0032403 IEA protein complex binding
GO:0034113 IEA heterotypic cell-cell adhesion
GO:0034687 IEA integrin alphaL-beta2 complex
GO:0035987 IEA endodermal cell differentiation
GO:0043113 IEA receptor clustering
GO:0043235 ISO receptor complex
GO:0043542 IEA endothelial cell migration
GO:0045121 IDA membrane raft
GO:0045123 IMP cellular extravasation
GO:0045429 IEA positive regulation of nitric oxide biosynthetic process
GO:0045766 IEA positive regulation of angiogenesis
GO:0046982 IEA protein heterodimerization activity
GO:0050730 IEA regulation of peptidyl-tyrosine phosphorylation
GO:0050798 IMP activated T cell proliferation
GO:0050839 IEA cell adhesion molecule binding
GO:0051092 IEA positive regulation of NF-kappaB transcription factor activity
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000302347 ITGB2-201 protein_coding Homo_sapiens 0 1844
ENST00000320216 ITGB2-010 protein_coding Homo_sapiens 0 893
ENST00000355153 ITGB2-001 protein_coding Homo_sapiens 0 1844
ENST00000397850 ITGB2-002 protein_coding Homo_sapiens 0 1844
ENST00000397852 ITGB2-005 protein_coding Homo_sapiens 0 1842
ENST00000397854 ITGB2-003 protein_coding Homo_sapiens 0 1452
ENST00000397857 ITGB2-004 protein_coding Homo_sapiens 0 1844
ENST00000475170 ITGB2-006 retained_intron Homo_sapiens 0 837
ENST00000479202 ITGB2-011 retained_intron Homo_sapiens 0 320
ENST00000498666 ITGB2-007 retained_intron Homo_sapiens 0 1007
ENST00000521987 ITGB2-018 processed_transcript Homo_sapiens 0 193
ENST00000522931 ITGB2-022 protein_coding Homo_sapiens 0 368
ENST00000523323 ITGB2-013 nonsense_mediated_decay Homo_sapiens 0 1840
ENST00000523663 ITGB2-024 protein_coding Homo_sapiens 0 394
ENST00000610622 ITGB2-202 protein_coding Homo_sapiens 0 1445

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