C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Down syndrome cell adhesion molecule
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000400454 DSCAM-001 ENSG00000171587 9606 - 21:40010999-40847139 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonLiverPlacentaTestisENST00000400454
Transcript ID Brain Colon Liver Placenta Testis
ENST00000400454 0.814±0.00 0.049±0.00 0.012±0.01 0.123±0.05 0.056±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001CT CIL_0001CT_0002 CGP 21:39867317-40847139
CIL_0001CW CIL_0001CW_0002 CGP 21:40010999-41282518

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005576 IEA extracellular region
GO:0005886 ISS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007155 IEA cell adhesion
GO:0007162 ISS negative regulation of cell adhesion
GO:0007399 TAS nervous system development
GO:0007626 IEA locomotory behavior
GO:0016020 TAS membrane
GO:0030424 ISS axon
GO:0030426 ISS growth cone
GO:0042327 IDA positive regulation of phosphorylation
GO:0048813 IEA dendrite morphogenesis
GO:0048842 IDA positive regulation of axon extension involved in axon guidance
GO:0060060 IEA post-embryonic retina morphogenesis in camera-type eye
GO:0070593 ISS dendrite self-avoidance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000056102 Dscam-001 protein_coding Mus_musculus 0 8506
ENSDART00000098038 dscamb-201 protein_coding Danio_rerio 0 2405
ENSDART00000125045 dscama-202 protein_coding Danio_rerio 0 2285
ENSDART00000136928 dscama-001 protein_coding Danio_rerio 0 2263
ENSDART00000098963 dscama-201 protein_coding Danio_rerio 0 2261

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