C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cyclin-dependent kinase inhibitor 1C (p57, Kip2)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000414822 CDKN1C-001 ENSG00000129757 9606 - 11:2883213-2885881 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLungMuscleOvaryTestisENST00000414822
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Lung Muscle Ovary Testis
ENST00000414822 16.551±0.00 1.227±0.00 1.228±0.00 16.756±0.00 11.688±0.00 1.525±0.00 5.123±0.00 0.759±0.00 3.370±0.00 11.797±0.00 4.576±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008A3 CIL_0008A3_0001 VISTA 11:2289701-2893486
CIL_0003FM CIL_0003FM_0002 CGP 11:2444684-2885881

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001501 IEA skeletal system development
GO:0001822 IEA kidney development
GO:0001890 IEA placenta development
GO:0004861 IEA cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005737 IDA cytoplasm
GO:0007050 IEA cell cycle arrest
GO:0007568 IEA aging
GO:0030099 IEA myeloid cell differentiation
GO:0030325 IEA adrenal gland development
GO:0030511 IMP positive regulation of transforming growth factor beta receptor signaling pathway
GO:0033673 IDA negative regulation of kinase activity
GO:0035264 IEA multicellular organism growth
GO:0042326 IDA negative regulation of phosphorylation
GO:0042551 IEA neuron maturation
GO:0043010 IEA camera-type eye development
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IGI positive regulation of transcription, DNA-templated
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0055123 IEA digestive system development
GO:0060065 IEA uterus development
GO:0060669 IEA embryonic placenta morphogenesis
GO:0071514 IEA genetic imprinting
GO:0071901 IEA negative regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000167912 Cdkn1c-202 protein_coding Mus_musculus 0 383
ENSMUST00000037287 Cdkn1c-201 protein_coding Mus_musculus 0 357

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