C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: hepatocyte nuclear factor 4, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000415691 HNF4A-006 ENSG00000101076 9606 + 20:44401301-44430500 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderColonKidneyPlacentaTestisENST00000415691
Transcript ID Bladder Colon Kidney Placenta Testis
ENST00000415691 3.221±0.00 4.706±0.00 9.363±0.00 0.013±0.00 0.402±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007R9 CIL_0007R9_0001 VISTA 20:44272530-44874028
CIL_0006S2 CIL_0006S2_0002 CGP 20:44336986-44432845

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001077 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001102 ISS RNA polymerase II activating transcription factor binding
GO:0003677 IDA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IEA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005102 IDA receptor binding
GO:0005504 IDA fatty acid binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006591 IMP ornithine metabolic process
GO:0006805 IMP xenobiotic metabolic process
GO:0007596 IDA blood coagulation
GO:0008270 IEA zinc ion binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0009749 ISS response to glucose
GO:0010467 TAS gene expression
GO:0019216 IDA regulation of lipid metabolic process
GO:0030308 IMP negative regulation of cell growth
GO:0030522 IEA intracellular receptor signaling pathway
GO:0031018 TAS endocrine pancreas development
GO:0042593 ISS glucose homeostasis
GO:0042803 IDA protein homodimerization activity
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0050796 ISS regulation of insulin secretion
GO:0055088 IMP lipid homeostasis
GO:0055091 ISS phospholipid homeostasis
GO:0060398 NAS regulation of growth hormone receptor signaling pathway
GO:0070328 ISS triglyceride homeostasis
GO:2000189 ISS positive regulation of cholesterol homeostasis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000018094 Hnf4a-201 protein_coding Mus_musculus 0 1648
ENSMUST00000109411 Hnf4a-001 protein_coding Mus_musculus 0 1648
ENSMUST00000131658 Hnf4a-003 processed_transcript Mus_musculus 0 684
ENSMUST00000137449 Hnf4a-004 protein_coding Mus_musculus 0 680

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