C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: hepatic nuclear factor 4, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000109411 Hnf4a-001 ENSMUSG00000017950 10090 + 2:163547187-163572910 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastHeartLiverLungMuscleOvaryPlacentaTestisENSMUST00000109411
Transcript ID Adipose Adrenal Brain Breast Heart Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000109411 0.014±0.01 0.024±0.01 0.003±0.00 0.081±0.07 0.017±0.00 11.242±7.50 0.098±0.04 0.010±0.00 0.101±0.04 2.889±2.54 0.020±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007R9 CIL_0007R9_0002 VISTA 2:163385776-163987192
CIL_0006S2 CIL_0006S2_0003 CGP 2:163492318-163572910
CIL_0002B3 CIL_0002B3_0002 CGP 2:163506808-163619013

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IEA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006629 IMP lipid metabolic process
GO:0007548 IMP sex differentiation
GO:0008270 IEA zinc ion binding
GO:0010470 IMP regulation of gastrulation
GO:0023019 IDA signal transduction involved in regulation of gene expression
GO:0030522 IEA intracellular receptor signaling pathway
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IDA sequence-specific DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0060395 IDA SMAD protein signal transduction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000316099 HNF4A-002 protein_coding Homo_sapiens 0 1873
ENST00000316673 HNF4A-001 protein_coding Homo_sapiens 0 1677
ENST00000372920 HNF4A-003 nonsense_mediated_decay Homo_sapiens 0 1705
ENST00000415691 HNF4A-006 protein_coding Homo_sapiens 0 1648
ENST00000443598 HNF4A-004 protein_coding Homo_sapiens 0 1500
ENST00000457232 HNF4A-005 protein_coding Homo_sapiens 0 1482
ENST00000609795 HNF4A-007 protein_coding Homo_sapiens 0 1334
ENST00000619550 HNF4A-201 protein_coding Homo_sapiens 0 1705

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