C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: isocitrate dehydrogenase 1 (NADP+), soluble
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000415913 IDH1-006 ENSG00000138413 9606 - 2:208236265-208254322 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartMuscleENST00000415913
Transcript ID Heart Muscle
ENST00000415913 0.522±0.00 0.315±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00045J CIL_00045J_0001 CGP 2:208165343-208266074
CIL_00014C CIL_00014C_0001 CGP 2:208236227-208358751

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0004450 IDA:IEA isocitrate dehydrogenase (NADP+) activity
GO:0005102 IPI receptor binding
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005777 IDA peroxisome
GO:0005782 TAS peroxisomal matrix
GO:0005829 IDA cytosol
GO:0006097 IEA glyoxylate cycle
GO:0006099 IEA tricarboxylic acid cycle
GO:0006102 IEA:IDA isocitrate metabolic process
GO:0006103 IDA 2-oxoglutarate metabolic process
GO:0006740 TAS NADPH regeneration
GO:0006749 IEA glutathione metabolic process
GO:0006979 IEA response to oxidative stress
GO:0008585 IEA female gonad development
GO:0014070 IEA response to organic cyclic compound
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042803 IPI protein homodimerization activity
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0048545 IEA response to steroid hormone
GO:0050661 IEA NADP binding
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000169032 Idh1-201 protein_coding Mus_musculus 0 1849
ENSMUST00000097709 Idh1-001 protein_coding Mus_musculus 0 1847
ENSMUST00000188109 Idh1-003 protein_coding Mus_musculus 0 824
ENSMUST00000188876 Idh1-004 protein_coding Mus_musculus 0 747
ENSMUST00000149310 Idh1-002 protein_coding Mus_musculus 0 566
ENSMUST00000186222 Idh1-006 protein_coding Mus_musculus 0 335

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