C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: MCF.2 cell line derived transforming sequence-like
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000421756 MCF2L-024 ENSG00000126217 9606 + 13:112979312-113096487 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungOvaryPlacentaTestisENST00000421756
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Ovary Placenta Testis
ENST00000421756 13.591±0.00 3.576±0.00 1.400±0.00 4.379±0.00 3.742±1.94 3.518±2.82 3.697±1.51 1.449±0.00 2.886±0.31 1.790±0.59 2.543±1.65 1.107±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00014E CIL_00014E_0001 CGP 13:112690329-113099739
CIL_0000RV CIL_0000RV_0001 CGP 13:112894378-113120681

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005615 IDA extracellular space
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0007264 TAS small GTPase mediated signal transduction
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000098927 Mcf2l-019 protein_coding Mus_musculus 0 3336
ENSMUST00000110866 Mcf2l-004 protein_coding Mus_musculus 0 3293
ENSMUST00000110867 Mcf2l-003 protein_coding Mus_musculus 0 3293
ENSMUST00000173099 Mcf2l-016 protein_coding Mus_musculus 0 3293
ENSMUST00000095456 Mcf2l-009 protein_coding Mus_musculus 0 3293
ENSMUST00000110879 Mcf2l-014 protein_coding Mus_musculus 0 3290
ENSMUST00000110871 Mcf2l-017 protein_coding Mus_musculus 0 3125
ENSMUST00000110876 Mcf2l-001 protein_coding Mus_musculus 0 3121
ENSMUST00000110873 Mcf2l-018 protein_coding Mus_musculus 0 2929
ENSMUST00000145067 Mcf2l-006 protein_coding Mus_musculus 0 2820
ENSMUST00000173006 Mcf2l-007 protein_coding Mus_musculus 0 2444
ENSMUST00000126905 Mcf2l-008 protein_coding Mus_musculus 0 2043
ENSMUST00000123811 Mcf2l-022 protein_coding Mus_musculus 0 625
ENSMUST00000134227 Mcf2l-015 protein_coding Mus_musculus 0 433
ENSMUST00000130302 Mcf2l-005 retained_intron Mus_musculus 0 396
ENSMUST00000156405 Mcf2l-002 processed_transcript Mus_musculus 0 392

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